In recent years, considerable effort in the field of operations research has been paid to optimizing airline operations, including the logistics of an airline’s fleet of aircraft. We focus on the problem of aircraft routing, which involves generating and selecting a particular route for each aircraft of a sub-fleet that is already assigned to a set of feasible sequences of flight legs. Similar ...

In recent years, considerable effort in the field of operations research has been paid to optimizing airline operations, including the logistics of an airline’s fleet of aircraft. We focus on the problem of aircraft routing, which involves generating and selecting a particular route for each aircraft of a sub-fleet that is already assigned to a set of feasible sequences of flight legs. Similar ...

Vehicle speed plays a significant role on fuel consumption and greenhouse gas emissions in freight transportation. We study a general joint routing and speed optimization problem with the goal of minimizing the total fuel, emission, and labor costs; the fuel consumption and emission rate is allowed to be an arbitrary strictly convex function of vehicle speed. We propose a novel set partitioning...

To evaluate the originality of a species for determining its conservation priority, most indices use the branching pattern and the branch length of a phylogenetic tree to represent the diversification pattern and the number of characters. One limitation of these indices is their lack of consideration of the dynamic process, such as character changes and distribution along lineages during evolut...

We consider a transport system problem which involves route planning for vehicles with containers attached, and cargo accommodation. The specific problem considered is the vehicle routing problem with loading constraints. Its input consists of a weighted undirected graph where vertices corresponds to clients and edges costs represents the cost to move the vehicle along that edge. Each vertex ha...

Male Long-Evans rats were administered nicotine bitartrate or sodium tartrate either during adolescence (p29-43) or adulthood (p80-94). Route of administration was via subcutaneously implanted osmotic pump (initial dose 2.0 mg/kg/day, free base). Five weeks following nicotine administration, brains were processed for Golgi-Cox staining. Medium spiny neurons from nucleus accumbens (NAc) shell we...

In this paper, we present new results on the automated generalization of performance-related heuristics learned for knowledge-lean applications. By rst applying genetics-based learning to learn new heuristics for some small subsets of test cases in a problem space, we study methods to generalize these heuristics to unlearned subdomains of test cases. Our method uses a new statistical metric cal...

A method for computationally efficient skeletonization of three-dimensional tubular structures is reported. The method is specifically targeting skeletonization of vascular and airway tree structures in medical images but it is general and applicable to many other skeletonization tasks. The developed approach builds on the following novel concepts and properties: fast curve-thinning algorithm t...