Bisphosphonate is used widely for osteoporosis treatment, but a rising concern is the risk of osteonecrosis after long-term bisphosphonate use. Such cases are increasing, suggesting a need for research to prevent and treat bisphosphonate-related osteonecrosis of jaws. A 63-year-old female took bisphosphonate (Fosamax(®)) for four years for treatment of osteoporosis and stopped medication two mo...

A case of spontaneous bone regeneration after mandibulectomy is presented. The patient was young and had a mandibular resection performed for a large fibroma. Only one of the condyles was preserved. Partial preservation of the periosteum may play an important role in rapid bone regeneration. In this case bone regeneration occurred only in mandibular regions where the periosteum could be preserved.

Abstract Introduction Oral cavity squamous cell carcinoma (OCSCC) is the most common malignancy in oral cavity. Two types of mandibular resections have been described: segmental mandibulectomy and marginal mandibulectomy. Both may a different impact over quality life, oncological prognosis, functional or aesthetic result. Objectives The aim this study was to systematically explore literature de...

Current treatment of odontogenic tumors (OT) ranges from simple enucleation by curettage or segmental resection. But the does not stop here, we need to think about rehabilitation patients. The Mandibular reconstruction can begin immediately postoperatively, but delayed be best option for treatment, because high risk recurrence in some OT, it is always a challenge. aim this study describe approa...

objective(s): there are many reports about the role of rostral ventromedial medulla (rvm) in modulating stress-induced analgesia (sia). in the previous study we demonstrated that temporal inactivation of rvm by lidocaine potentiated stress-induced analgesia. in this study, we investigated the effect of permanent lesion of the rvm on sia by using formalin test as a model of acute inflammatory pa...