Since Partin introduced the analysis of prostate-specific antigen, clinical T-stage and Gleason scores to estimate the risk of progression in men with localised prostate cancer, our understanding of factors that modify this risk has changed drastically. There are now multiple risk stratification tools available, including look-up tables, risk stratification/classification analyses, regression-t...

INTRODUCTION Pregnant women with thromboembolic diseases, previous thrombotic episodes or thrombophilia family history were supervised in a multidisciplinary Obstetrics/ Hematology consultation in Centro Hospitalar São João EPE, Porto, Portugal. For the evaluation and medication of these women, a risk stratification scale was used. PURPOSES The aim of this study was to validate a Risk Stratif...

Sudden cardiac death (SCD) is a serious public health problem; the annual incidence of out-of-hospital cardiac arrest in North America is approximately 166,200. Identifying patients at risk is a difficult proposition. At the present time, left ventricular ejection fraction (LVEF) remains the single most important marker for risk stratification. According to current guidelines, most patients wit...

Kathryn A Glatter*, Nipavan Chiamvimonvat, Matti Viitasalo, Qing Wang, and Dipika Tuteja Department of Cardiology,University of California, Davis, Sacramento, CA 95817, USA (KAG, NC, DT); Department of Cardiology,Helsinki University Hospital, Helsinki, Finland (MV); and Center for Cardiovascular Genetics and Department of Molecular Cardiology Cardiology, Cleveland Clinic Foundation, Cleveland, ...

Silvia G. Priori, MD, PHD,*†‡ Maurizio Gasparini, MD,§ Carlo Napolitano, MD, PHD,*‡ Paolo Della Bella, MD, Andrea Ghidini Ottonelli, MD,¶ Biagio Sassone, MD,# Umberto Giordano, MD,** Carlo Pappone, MD,†† Giosuè Mascioli, MD,‡‡ Guido Rossetti, MD,§§ Roberto De Nardis MD, Mario Colombo, MS¶¶ Pavia, Rozzano, Milano, Lido di Camaiore, Bentivoglio, Palermo, Ravenna, Bergamo, Cuneo, and Vicenza, Ital...

syndromes aims to identify those patients at greatest risk of recurrent ischaemic events who might benefit prognostically from further investigation and treatment. Unfortunately, however, none of the clinical or investigative markers currently available has suYcient diagnostic power to identify all high risk patients while excluding those at negligible risk. Moreover, for patients judged to be ...

Arrhythmic sudden cardiac death (SCD) may be caused by ventricular tachycardia/fibrillation or pulseless electric activity/asystole. Effective risk stratification to identify patients at risk of arrhythmic SCD is essential for targeting our healthcare and research resources to tackle this important public health issue. Although our understanding of SCD because of pulseless electric activity/asy...