Right ventricular (RV) hypertrophy is common in patients with hypertrophic cardiomyopathy (HCM), and is associated with more severe disease. Conventional surgical strategies such as the traditional Morrow procedure pose a particularly high risk to patients with severe hypertrophy and RV obstruction, for whom the most appropriate therapeutic approach has not yet been established. We have propose...

cryoablation to treat atrial fibrillation. J Interv Card Electrophysiol 2004; 11:117–126. 32. Scholten MF, Kimman GJ, Janse PA, Thornton AS, Theuns DAMJ, Jordaens LJ. Electrical Isolation of pulmonary veins using cryothermal energy: study design and initial results.NethHeart J 2003;453–458. 33. Natale A, Pisano E, Shewchik J, Bash D, Fanelli R, Potenza D, Santarelli P, Schweikert R, White R, Sa...

UNLABELLED Between May 1974 and December 1993, 37 patients (0.75%) with a double-chambered right ventricle underwent surgical repair. The patients ranged in age from 11 months to 12 years (mean 4 +/- 1.1 years). Cardiac catheterization was performed in 36 patients. The proximal right chamber pressure was 118 +/- 10 mmHg and the mean ventricular gradient pressure was 75 +/- 10 mmHg. A ventricula...

Abnormal development of the arterial pole of the heart underlies a significant fraction of congenital heart defects. Critical steps in arterial pole development are formation of the myocardial outflow tract (or conotruncal region) and its subsequent division into separate left and right ventricular outlets. Division of the cylindrical outflow tract is a complex morphogenetic process driven by c...

In a previous study the possibility that tetralogy of Fallot and transposition of the great arteries may arise as a result of embryonic arrests in the normal rotation of the junction of the outflow tract and the great arteries was investigated. The results suggested that the development of other transposition complexes such as double-outlet right ventricle might also be related to arrests in th...

1 of 2 DESCRIPTION A murmur was noted in a 2-year-old patient who was otherwise asymptomatic. The patient was born by caesarean section at 37 weeks gestation. No signifi cant family history was present. Clinical examination revealed a continuous murmur at the sternal edge. Echocardiography did not reveal any abnormality. Cardiac catheterisation revealed a communication between the right coronar...

Introduction: Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-2 (Nox2) is one of the predominant sources of ROS production during myocardial ischemia-reperfusion and can be induced by angiotensin II. The evidence suggests that pharmacological blockers of renin-angiotensin system can exert direct tissue effects independent of their ability to regulate blood pressure. The mechanism...

PURPOSE It is unclear if prolonged contrast media injection, to improve right ventricular visualization during coronary CT angiography, leads to increased detection of right ventricle pathology. The purpose of this study was to evaluate right ventricle enhancement and subsequent detection of right ventricle disease during coronary CT angiography. MATERIALS AND METHODS 472 consecutive patients...