Three cases of Rift Valley fever in human individuals are reported. The virus was recovered from the respiratory tract of the patients and was transmitted to ferrets by the intranasal route. The experimental disease so produced in ferrets is characterized by fever, marked pulmonary lesions, and hemorrhagic phenomena. The results indicate that the virus of Rift Valley fever belongs to the group ...

The ecodesign of urban environments at different spatial scales6 is an emerging topic fostered by the research on ecodesign and urban sustainability. Urban areas and environments are expanding worldwide. Statistics of urban population share reach figures of 70% in Europe, America and Oceania and 50% globally1. This ever-increasing urban population is likely to grow even more2. With this unprece...

Antiviral Activity of Favipiravir (T-705) Against Lethal Rift Valley Fever Virus Infection in Hamsters

Rift Valley fever (RVF) is a zoonotic viral disease that can affect a variety of species, including ruminants and camels, causing high mortality in young animals and/or abortions in adults. The RVF virus is endemic mainly in subSaharan Africa, but it has also been seen in North Africa, and may have become established in Egypt. There are concerns that this virus might be spreading, after outbrea...

Since the original description of Rift Valley fever in sheep, cattle and man in the Rift Valley in Kenya in 1931, very little has been published on the disease in cattle. This report deals with the macroscopic and microscopic pathology of field cases of Rift Valley fever in 22 adult cattle, 8 calves and 8 aborted foetuses. The microscopic liver lesions in 13 adult cattle were characterized by m...

In early September 2012, a human case of RVF was reported in Mauritania. By 30 October 2012, a total of six regions had been affected with 34 human cases of RVF, including 17 deaths. Only the southern regions of Mauritania, those closest to the usual enzootic areas along the Senegal River, seem to have been involved in this event. Although no active cases in animals have been reported to the Wo...

6. Innis B, Nisalak A, Nimmannitya S, Kusalerdchariya S, Chongswasdi V, Suntayakorn S, et al. An enzyme-linked immunosorbent assay to characterize dengue infections where dengue and Japanese encephalitis co-circulate. Am J Trop Med Hyg 1989;40:418–27. 7. Guzman MG., Kouri G., and Halstead SB. Do escape mutants explain rapid increases in dengue case-fatality rates within epidemics? Lancet 2000;3...

Rift Valley fever (RVF) is a peracute or acute zoonotic disease of domestic ruminants. The virus is currently confined to the African continent and Arabian Peninsula. It is caused by a single serotype of a mosquito-borne virus of the Bunyaviridae family (genus Phlebovirus). The disease occurs in climatic conditions favouring the breeding of mosquito vectors and is characterised by abortion, neo...

Vet Med Today: Zoonosis Update 883 R Valley fever virus is a mosquito-borne pathogen of livestock and humans that historically has been responsible for widespread and devastating outbreaks of severe disease throughout Africa and, more recently, the Arabian Peninsula. The virus was first isolated and RVF disease was initially characterized following the sudden deaths (over a 4-week period) of ap...

About 125 130 million years ago South America began to separate from Africa and as the continents drifted apart, an extensive rift valley was formed, containing large lakes with abundant organic material that had washed off the adjacent highlands. In Angola, these sediments are known as the Bucomazi formation, an exceedingly rich oil and gas source rock. The rift valleys are similar to the pres...