The nature of the protective substance in ribosomal ribonucleic acid and protein extracts of Salmonella has been investigated. The results of experiments in which vaccines were prepared from isogenic strains and strains with defects in lipopolysaccharide synthesis show that O antigens contaminate both ribonucleic acid and protein ribosomal extracts, and are responsible for at least part of thei...

In an earlier investigation from this laboratory (I), prostatic phosphomonoesterase was used for the partition of the phosphomonoester and phosphodiester groups in ribonuclease digests. It was shown that the inorganic phosphate formed during incubation of ribonuclease digests with phosphatase originated practically exclusively from the acid-stable (pyrimidine) nucleotide groups of ribonucleic a...

EKSTEEN, P. A . L. & HUISMAN S, H. Interferon induction by bluetongue virus and bluetongue virus ribonucleic acid. Onderstep oort]. vet . R es. 39(3), 125-132 (1972). The stimulation of interferon synthesis by bluetongue virus and by bluetongue virus ribonucleic acid was investigated in order to determine if there is a difference in the mechanism of induction. The molecular mass of the interfer...

Ribonucleic acid isolated from cerebral cortex of mature male and female rats was fractionated by chromatography on methylated albumin Kieselguhr columns or by sucrose gradient centrifugation. Three principal fractions were obtained with analytical ultracentrifuge s~o,~ values of 4, 17, and 28. By comparison with ribonucleic acid prepared from purified rat brain ribosomes, the 17 S and 28 S fra...

Syringomycin, a wide-spectrum antibiotic produced by strains of Pseudomonas syringae which cause bacterial canker of peach, was able to bind to salmon sperm and calf thymus deoxyribonucleic acid but not to calf thymus histone; it also inhibited ribonucleic acid polymerase activity. These abilities to bind to deoxyribonucleic acid and to inhibit ribonucleic acid polymerase were inactivated when ...

1. The unfertilized Arbacia egg contains an average of 20gamma x 10(-3) ribonucleic acid and 0.7 to 1gamma x 10(-3) desoxyribonucleic acid. 2. During the first 24 hours of development, the amount of ribonucleic acid per embryo remains practically unchanged whereas that of desoxyribonucleic acid steadily increases. At the end of this period, the amount of desoxyribonucleic acid per embryo is 10 ...