Immunotherapy is the only treatment for allergy that has the potential to alter the natural course of the disease. Sublingual immunotherapy (SLIT) for grass pollen-induced rhino-conjunctivitis has been developed to make immunotherapy available to a broader group of allergic patients. In the largest clinical programme ever conducted with allergen-specific immunotherapy, over 1,700 adults and 260...

OBJECTIVE This study aims at defining the incidence of rhino-bronchial syndrome (RBS) in children in order both to verify the influence of nasal obstructions on the disease and to determine therapeutic strategies which may cure the syndrome effectively at its early stage. METHODS The investigation includes 128 non-allergic children with obstructive disorders (adenoid hypertrophy, septal devia...

As high performance design is becoming more desirable in the field of architecture, the need for supporting architects with environmental analysis tools is also growing. Rhino/Grasshopper is one of the most widely used platforms that are used by designers today. There are already a number of environmental plugins developed for Rhino/Grasshopper. However, Ladybug offers several advantages that a...

Growing on a plastic dish, the stem cells don’t look like much. Widely spaced, with jagged borders, they resemble distantly separated islands under the bright light of a microscope. But Garrett Vygantas believes cells like these could save the rhinoceros from extinction. Induced pluripotent stem (iPS) cells have the ability to mature into any type of cell in the body. Vygantas’s company, Cerato...

Comparisons of recent estimations of home range sizes for the critically endangered black rhinoceros in Hluhluwe-iMfolozi Park (HiP), South Africa, with historical estimates led reports of a substantial (54%) increase, attributed to over-stocking and habitat deterioration that has far-reaching implications for rhino conservation. Other reports, however, suggest the increase is more likely an ar...

A 12-year-old female patient started with sudden abdominal pain, polyuria, polydipsia, anorexia and a drop in conscience level. She was diagnosed with untreated type I diabetes mellitus (diabetic acidosis), with blood sugar of 508 mg/dl upon hospital admission. After one week in the hospital, she started having eyelid ptosis, facial pain, converging strabismus, left side epistaxis and a progres...

BACKGROUND One fourth of the adult population in Europe suffer from respiratory allergy. Subcutaneous-allergen-specific-immunotherapy (SCIT) has long-term disease modifying effect on disease specific Health-Related Quality of Life (HRQoL). The purpose of this study was to assess the effect of SCIT on alternative disease outcomes in patients with grass-pollen and/or house dust mite induced aller...

introduction rhino-orbito-cerebral mucormycosis is a progressive angioinvasive fungal disorder which almost always complicates immunocompromised patients. case presentation we described a case of fulminant rhino-orbito-cerebral mucormycosis in a 65-year-old woman, who presented with progressive neurological deficits due to involvement of orbital apex and the central nervous system by local inva...