objective(s): repaglinide (rg) is an antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus. it has a good safety and efficacy profile in diabetic patients with complications in renal impairment and is an appropriate treatment choice, even for individuals with more severe degrees of renal malfunctions. the aim of the present study was to examine the protective...

Interpreting RG flows as dynamical systems in the space of couplings we produce a variety of constraints, global (topological) as well as local. These constraints, in turn, rule out some of the proposed RG flows and also predict new phases and fixed points, surprisingly, even in familiar theories such as O(N) model, QED3, or QCD4. © 2017 Published by Elsevier B.V. This is an open access article...

A system with many degrees of freedom can be characterized by a covariance matrix; principal components analysis (PCA) focuses on the eigenvalues of this matrix, hoping to find a lower dimensional description. But when the spectrum is nearly continuous, any distinction between components that we keep and those that we ignore becomes arbitrary; it then is natural to ask what happens as we vary t...

Let S(RG) be a normed Sylow p-subgroup in a group ring RG of an abelian group G with p-component Gp and a p-basic subgroup B over a commutative unitary ring R with prime characteristic p. The first central result is that 1 + I(RG;Bp) + I(R(p)G;G) is basic in S(RG) and B[1 + I(RG;Bp) + I(R(p )G;G)] is p-basic in V (RG), and [1 + I(RG;Bp) + I(R(p )G;G)]Gp/Gp is basic in S(RG)/Gp and [1 + I(RG;Bp)...

High resolution spectra of (CO2)2-Rg trimers (Rg = Ne, Ar, Kr, and Xe) in the region CO2 ν3 fundamental (≈2350 cm−1) are reported, using a tunable OPO laser source to probe pulsed supersonic slit jet expansion. These transitions tend be hidden among stronger due other species, such as CO2-Rg (CO2)2. Each trimer consists (CO2)2 unit which is similar free carbon dioxide dimer (planar parallel sta...

Dimerization of rhamnogalacturonan-II (RG-II) via boron cross-links contributes to the assembly and biophysical properties of the cell wall. Pure RG-II is efficiently dimerized by boric acid (B(OH)3 ) in vitro only if nonbiological agents for example Pb(2+) are added. By contrast, newly synthesized RG-II domains dimerize very rapidly in vivo. We investigated biological agents that might enable ...

The discovery of roles for arginine methylation in intracellular transport and mRNA splicing has focused attention on the methylated arginine-glycine (RG)-rich domains found in many eukaryotic RNA-binding proteins. Sequence similarity among these highly repetitive RG domains, combined with interactions between RG-rich proteins, raises the question of whether these regions are general interactio...