نتایج جستجو برای: restriction modification system

تعداد نتایج: 2396706  

2005
I. Kobayashi

A restriction (R) endonuclease recognizes a specific DNA sequence and introduces a double-strand break (Fig. 1A). A cognate modification (M) enzyme methylates the same sequence and thereby protects it from cleavage. Together, these two enzymes form a restriction-modification system. The genes encoding the restriction endonuclease and the cognate modification enzyme are often tightly linked and ...

Journal: :Journal of bacteriology 2002
Marc Naderer Jessica R Brust Dieter Knowle Robert M Blumenthal

The flow of genes among prokaryotes plays a fundamental role in shaping bacterial evolution, and restriction-modification systems can modulate this flow. However, relatively little is known about the distribution and movement of restriction-modification systems themselves. We have isolated and characterized the genes for restriction-modification systems from two species of Salmonella, S. enteri...

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