OBJECTIVE To investigate the occurrence of restricted diffusion in vanishing white matter, the affected structures,the time of occurrence in the disease course, and the histopathologic correlate. DESIGN Retrospective observational study. PATIENTS Forty-six patients with vanishing white matter. SETTING VU University Medical Center. MAIN OUTCOME MEASURES We evaluated all available diffusi...

BACKGROUND AND PURPOSE Diffusion-weighted imaging (DWI) is useful in diagnosing bacterial brain abscesses, but DWI features of fungal brain abscesses have not been characterized. Because fungal abscesses are not purulent, we hypothesized that their DWI characteristics are distinct from those of bacterial abscesses. METHODS We reviewed clinical, neuropathologic and neuroimaging findings of pat...

Diffusion weighted magnetic resonance imaging has risen to the forefront of imaging for acute stroke. However, the differential diagnosis of restricted diffusion is wide and includes ischemia, metabolic derangements, infections, and highly-cellular masses. We present a case of central nervous system (CNS) candidiasis presenting radiographically as bilateral punctate areas of restricted magnetic...

Single particle tracking was used to evaluate lateral motions of individual FLAGtagged human luteinizing hormone (LH) receptors expressed on Chinese hamster ovary (CHO) cells and native LH receptors on both KGN human granulosa-derived tumor cells and M17 human neuroblastoma cells before and after exposure to human chorionic gonadotropin (hCG). Compared to LH receptors on untreated cells, LH rec...

to a wide range of neurological symptoms, ranging from headaches, dizziness and altered mental status to coma. The basis for this is thought to be hypoxia. Carbon monoxide competes with oxygen for binding to hemoglobin (Hb) and once bound, shifts the oxyhemoglobin dissociation curve to the left, thus impairing off-loading of oxygen molecules, leading to hypoxia . A sizable minority of CO poison...

We study the dynamics of a system made up of particles of two different species undergoing irreversible quadratic autocatalytic reactions: A + B → 2A. We especially focus on the reaction velocity and on the average time at which the system achieves its inert state. By means of both analytical and numerical methods, we are also able to highlight the role of topology in the temporal evolution of ...