PURPOSE Because of diagnostic improvements in the evaluation of uterine anomalies, more patients desirous of pregnancy come to clinicians with identified uterine anomalies. It is desirable for the family physician, internist, and obstetrician/gynecologist to provide accurate information during preconceptional counseling of these patients. This review attempts to provide a concise summary of the...

BACKGROUND Preimplantation genetic diagnosis (PGD) has been stated to improve live birth rates compared with natural conception in couples with recurrent miscarriage (RM) carrying a structural chromosome abnormality. It is unclear to what extent this claim can be substantiated by evidence. A systematic review of the literature was performed on the reproductive outcome of these couples after nat...

Adverse health effects and reproductive hazards at the workplace are an issue of increasing health concern and more than 1000 chemicals at workplace have been demonstrated to have adverse effects in animals. However such studies are limited in humans. Since data on reproductive epidemiology in traffic policemen exposed to automobile exhaust is limited, a study on the reproductive endpoints of t...

OBJECTIVE To evaluate whether methotrexate (MTX) compromises ovarian reserve and future reproductive outcome in women undergoing assisted reproductive technology (ART), when it is used as first-line treatment for ectopic pregnancy (EP). DESIGN Prospective, observational study. SETTING University-affiliated private IVF unit. PATIENT(S) Twenty-five women undergoing IVF-ICSI who were treated...

STUDY QUESTION How do randomised controlled trials (RCTs) in reproductive medicine report maternal and neonatal outcomes, specifically singleton live birth? SUMMARY ANSWER Despite the widespread appeal to use singleton live birth as the outcome measure in subfertility trials, 80% of RCTs fail to do so, and fail to report on neonatal and maternal outcomes. WHAT IS KNOWN ALREADY The aim of re...

INTRODUCTION Patients with uterine malformations have decreased reproductive potential and an unfavourable reproductive outcome starting even from the first pregnancy. Patients with untreated uterine malformations have a term delivery rate of 40%-65%. Hysteroscopic metroplasty is a standard, safe and minimally invasive method for treatment of uterine malformations, which provides a normal uteri...

ObjectiveTo assess the efficacy of fertility-sparing surgery (FSS) in terms reproductive outcomes by following FSS for borderline ovarian tumors (BOTs) and comparing safety versus radical (RS).DesignNationwide cohort study based on prospectively recorded data.SettingSweden.Patient (s)All women age (18–40 years) treated Sweden stage I BOT with use or RS from 2008 to 2015, identified Swedish Qual...