CONTEXT Patients with end-stage renal disease can easily acquire a hepatitis C virus (HCV) infection via several ways. An HCV infection is difficult to treat after renal transplantation due to the conflicting actions of immunosuppressant therapy to maintain the function of the transplanted kidney and viricidal interferon (IFN) or ribavirin (RBV) treatment. Antiviral therapy requires great cauti...

the relation between microchimerism and allograft tolerance is still a mystery. in this study we determined the presence of peripheral blood microchimerism (pbmc) in female renal transplant recipients from living male donors with second round polymerase chain reaction (pcr). second round pcr was used to find y chromocome products. the degree of pbmc in renal transplant recipinents must be below...

renal actinomycosis is a rare infection, and actinomycosis mostly acts as a normal flora in mouth, colon and vagina. we present a case of 56 years old man, who referred to our center for renal transplantation with kidney stone and diagnosed  with renal actinomycosis.  this case has risen possibility of rare infection that can be considered in the setting of renal transplantation.

conclusions chronic renal disease contributes to sarcopenia, which may develop at an earlier age in rtr. background chronic kidney disease can lead to sarcopenia; however, no study has described sarcopenia in the patients undergoing renal transplantation. objectives the aim of the present study was to assess the prevalence of sarcopenia in renal transplant recipients (rtr) and to evaluate the d...

conclusions our study demonstrates that preconditioning of kidney with chronic ptu administration protects renal tissue against iri and this phenomenon was mediated through no system. the results suggest a potential indication for using ptu to protect the kidney before transplantations and to reduce the risk of tissue rejection afterwards. background renal ischemia/reperfusion injury (iri) is a...

Immunosuppressive medicines are characterized by specific pharmacokinetic profile which requires therapy monitoring by means of measuring their blood concentrations. Therapy monitoring, by means of determining blood concentration of the medicine, enables application of an optimal individual immunosuppressive therapy. Due to its variable pharmacokinetics, and small therapeutic index and potentia...

OBJECTIVE Renal transplantation is an outstanding therapy for end-stage renal failure and has been shown to increase life expectancy and quality of life, while reducing medical expenditure. The presence of IgM antibodies in recipient serum is not a contraindication for renal transplantation. However, the presence of this antibody may have significant clinical implications. IgM autoantibodies ha...

Renal transplantation is considered one of the best long-term therapies for chronic renal failure, but unfortunately the incidence of malignancy significantly increases in renal transplant recipients. We analyzed nine cases of malignancy in 200 renal transplant recipients occurring in a 12-year follow-up in Imam hospital of Tehran University, Tehran, Iran. According to this study, the organ...