Introduction Malaria is a common tropical infection. It is a kind of mosquito borne infection. The pathogen is the protozoa in Plasmodium spp. The patient usually gets acute febrile illness after get mosquito bite at malarial area. The infection can still be seen in several countries. The cases can be presently seen not only in tropical but nontropical countries due to good transportation syste...

OBJECTIVE The goal of this investigation was to determine whether more aggressive vancomycin dosing is associated with greater risk for renal toxicity in patients with health care-associated pneumonia (HCAP) attributed to methicillin-resistant Staphylococcus aureus (MRSA). METHODS This was a retrospective, single-center, observational cohort study. The following information was obtained for a...

OBJECTIVES The purpose of this study was to document the incidence and extent of cardiovascular toxicity among advanced renal cell carcinoma patients treated with newer targeted cancer agents. BACKGROUND The potential for targeted cancer agents to induce cardiovascular toxicity has been increasingly recognized, but the overall incidence and extent of toxicity have not been well characterized....

stachys lavandulifolia ( s. lavandulifolia ) is a plant that has been widely used as an herbal medicine in iran. unfortunately, despite the prevalent medicinal uses of the plant, there are no reports on the possible toxic effects of s. lavandulifolia . in the present study the potential toxicity of s. lavandulifolia after acute and sub-chronic administration in rats was evaluated. rats were ora...

Background: Levofloxacin is a fluoroquinolone antibiotic that has broad-spectrum antimicrobial activity, but it may induce kidney dysfunction. Clove oil (Oleum caryophylli) has antioxidant properties that may alleviate levofloxacin toxicity. This study aimed to examine the protective effect of clove oil on levofloxacin-induced nephrotoxicity in rat animal models. Methods: A total of 24 male ra...

The role of the tubular reabsorption of aminoglycosides in nephrotoxicity was considered. The tubular reabsorption rate, fractional reabsorption, and net balance, expressed as the excreted to infused aminoglycoside ratio, were concomitantly studied in male rabbits by continuous infusion of gentamicin, netilmicin, dibekacin, and amikacin. Aminoglycoside nephrotoxicity was evaluated by creatinine...