gestational choriocarcinoma usually occurs following an intrauterine pregnancy. we report a case of metastatic choriocarcinoma to the left kidney and lungs with long term intermittent amenorrhea and vaginal bleeding after a normal vaginal delivery. a 43 year old rural woman presented with three years intermittent amenorrhea and vaginal bleeding following normal vaginal delivery. she also compla...

background: monitoring of phenotypic characteristics of t-lymphocytes in peripheral blood is commonly performed to give the clinical parameters in the management of kidney transplant recipients.   objective: to predict rejection in renal transplantation by immune parameters. methods: 16 non-diabetic kidney transplant candidates (4 females and 12 males, age = 20-65 yr, first time transplant) wer...

background and objective: cystinosis is a rare inherited disease that leads to renal failure. fanconi syndrome is the major renal involvement in cystinosis patients. renal transplantation is the treatment of choice in cystinosis children with end-stage renal disease (esrd).  the study aimed to assess the outcome of renal transplantation in iranian children with cystinosis. methods: this retrosp...

these investigations indicate that the anterior layer of the renal fascia continues across the midline of the body in front of the aorta and inferior vena cava to become continuous with a similar layer on the opposite side of the body. the posterior layer of the renal fascia blends with the fascia covering the psoas major especially at the medial and lateral edges of this muscle. but, in additi...

absractthis study investigated a 63-day boy with end stage renal disease and abdominalcysts. the antenatal sonography detected anhydraminos, posterior urethral valve,and cystic dysplastic kidneys. voiding cystourethrogram revealed two obstructivegiant diverticula which at first looked like enlarged renal pelvis. the patient had persistenturinary tract infection and perforation of diverticula. t...

Background Few results have shown that renal parenchymal echogenicity increases in pediatric patients with no concurrent renal diseases. This study aimed to investigate the relation between non-renal diseases and renal cortical echogenicity in children with acute abdominal pain. Materials and Methods  This cross- sectional study was conducted among 100 children referred to Amirkola Children’s ...

Background: Primary infection with BK virus (BKV) is occurred during childhood and usually asymptomatic, but after initial infection, BKV may persist lifelong in the kidney and genitourinary tract. Reactivation may occur in individuals with compromised immunity such as renal transplant recipients. Due to the role of BKV in BK virus-associated nephropathy (BKVAN) and po...

Objective(s): Empagliflozin, a sodium-glucose cotransporter-2 (SGLT-2) inhibitor, possesses verified anti-inflammatory and anti-oxidative stress effects against diabetic nephropathy. The present investigation aims to examine empagliflozin effects on the renal levels of high mobility group box-1 (HMGB1), a potent inflammatory cytokine, and its respective receptor toll-like receptor-4 (TLR-4) in ...

Cyclooxygenase (COX), the key enzyme for synthesis of prostaglandins, exists in two isoforms (COX-1 and COX2). COX-1 is constitutively expressed in the gastrointestinal tract in large quantities and has been suggested to maintain mucosal integrity through continuous generation of prostaglandins. COX-2 is induced predominantly during inflammation. On this premise selective COX-2 inhibitors not a...

objective: dalbegia saxatilis (d.saxatilis) is used as a decoction in traditional medicine for ailments such as cough, small pox, skin lesions, bronchial ailments and toothache. this study is aimed at evaluating the toxic effect of methanol leaf extract of d.saxatilis on renal function. materials and methods: wistar rats of both sexes were divided into four groups of five: control animals (grou...