A carrier system based on nanoporous silica (SBA-15) with magnetic nanoparticles of CoFe2O4 was synthesized via the impregnation of cobalt salt, iron salt and citric acid with as-synthesized SBA-15. The obtained samples were characterized by small angle X-ray scattering (SAXS), N2 adsorption/desorption, scanning electron microscopy (SEM), vibrating sample magnetometer (VSM) and ultraviolet (UV)...

blood pressure rises rapidly upon awakening and maybe responsible, in part, for the increased incidence of myocardial infarction and stroke during the morning hours. the aim of the present study was, therefore, to develop a novel chronotherapeutic formulation of metoprolol tartrate (mt) for night time dosing providing maximum effect in the morning hours. core tablets contained mt, sodium chlori...

In this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. The effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...

In this study, tretinoin microemulsion has been formulated based on phase diagram studies by changing the amounts and proportions of inactive ingredients, such as surfactants, co-surfactants and oils. The effects of these variables have been determined on microemulsion formation, particle size of the dispersed phase and release profile of tretinoin from microemulsion through dialysis membrane. ...

Objective(s): Nowadays hydrogels are one of the upcoming classes of polymer-based controlled-release drug delivery systems. Temperature and pH-responsive delivery systems have drawn much attention because some diseases reveal themselves by a change in temperature and/or pH. The objective of this work is to prepare and characterize composite membrane using responsive nanoparticles into a polymer...

thymol, an important and advantageous component of many essential oils, has been applied as an antimicrobial agent in animals. to increase the duration of action of this compound in ruminants, it was decided here to prepare a controlled release carrier for thymol. hydroxy propyl methyl cellulose (hpmc) and ethyl cellulose (ec) were used as the matrix polymer here. mixtures of thymol with eight ...

double emulsion solvent evaporation technique is one of the most attractive methods used to prepare micro and nanoparticles in pharmaceutical areas of interest, but because of the effects of many formulation factors on the size and release behavior of the fabricated particles, optimization of the formulation factors is needed. in this study various parameters including technical and composition...

A carrier system based on nanoporous silica (SBA-15) with magnetic nanoparticles of CoFe2O4 was synthesized via the impregnation of cobalt salt, iron salt and citric acid with as-synthesized SBA-15. The obtained samples were characterized by small angle X-ray scattering (SAXS), N2 adsorption/desorption, scanning electron microscopy (SEM), vibrating sample magnetometer (VSM) and ultraviolet (UV)...