نتایج جستجو برای: relative potency

تعداد نتایج: 412692  

Journal: :Japanese journal of medical science & biology 1965
H KONDO S KONDO S SADAHIRO K YAMAUCHI A OHSAKA R MURATA

Attempts were made to establish an authentic method for assay of the antilethal potency of Habu antivenine. In spite of its wide use the expression of the antivenine potency in •ganimal nimal unit•h is not reasonable. The expression of the antivenine potency as the relative potency is not valid either so far as a crude venom is used as test toxin, since the neutralization curves of various anti...

Journal: :Toxicology in vitro : an international journal published in association with BIBRA 2010
Jessica C Hervé Doug Crump John P Giesy Matthew J Zwiernik Steven J Bursian Sean W Kennedy

Ethoxyresorufin O-deethylase (EROD) activity was measured in primary cultures of ring-necked pheasant (Phasianuscolchicus) and Japanese quail (Coturnix japonica) embryonic hepatocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), 2,3,4,7,8-pentachlorodibenzofuran (PeCDF) and 2,3,7,8-tetrachlorodibenzofuran (TCDF) for 12, 24, 36 and 48 h. In ring-necked pheasant hepatocytes there was a ...

Journal: :Contact dermatitis 2007
David A Basketter Frank Gerberick Ian Kimber

For the prediction of skin sensitization potential, the local lymph node assay (LLNA) is a fully validated alternative to guinea-pig tests. More recently, information from LLNA dose-response analyses has been used to assess the relative potency of skin sensitizing chemicals. These data are then deployed for risk assessment and risk management. In this commentary, the utility and validity of the...

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