Methamphetamine's widepread abuse and concerns that it might increase Parkinson's disease led us to assess if the reported loss of dopamine transporters (DAT) in methamphetamine abusers (MA) reflected damage to dopamine neurons. Using PET with [(11)C]cocaine to measure DAT, and with [(11)C]raclopride to measure dopamine release (assessed as changes in specific binding of [(11)C]raclopride betwe...

The aim of this study was to examine the temporal relationship between behaviorally measured visual thresholds, photoreceptor degeneration and dysfunction, synaptic and neuronal morphology changes in the retina in the S334ter line 4 rat. Specifically, we examined the optokinetic tracking (OKT) behavior in S334ter rats daily and found that OKT thresholds reflected normal values at eye opening bu...

introduction:   the daf is a large persian frame drum used as a musical instrument in both popular and classical music which can induce a percussive sound at low frequencies (146–290 hz) with peaks of up to 130 dbspl. the percussive sounds have a power distribution in the region of saccular sensitivity. in view of the saccular stimulation by sound in humans, we decided to use cervical vestibula...

objective: dietary changes playmajor risk roles in oxidative stress andcardiovascular disease and modulate normal metabolic function. the present study was designed to investigate the ameliorative potential of different extracts of hemidesmus indicus to experimental high-fat diet in wistar rats, and their possible mechanism of action.  materials and methods: male wistar rats were divided into 6...

We theoretically study reflection of light by a phase-conjugating mirror preceded by a partially reflecting normal mirror. The presence of a suitably chosen normal mirror in front of the phase conjugator is found to greatly enhance the total phase-conjugate reflected power, even up to an order of magnitude. Required conditions are that the phase-conjugating mirror itself amplifies upon reflecti...

800x600 unfortunately, at present, degenerative retinal diseases such as retinitis pigmentosa remains untreatable. patients with these conditions suffer progressive visual decline resulting from continuing loss of photoreceptor cells and outer nuclear layers. however, stem cell therapy is a promising approach to restore visual function in eyes with degenerative retinal diseases such as retiniti...