PURPOSE To differentiate between keratoconus and contact lens-related corneal warpage by combining focal change patterns in anterior corneal topography, pachymetry, and epithelial thickness maps. METHODS Pachymetry and epithelial thickness maps of normal, keratoconus, and warpage, and forme fruste keratoconus (FFK) eyes were obtained from a Fourier-domain optical coherence tomography (OCT). E...

We report a familial case of keratoconus with corneal granular dystrophy. The mother and first son have both keratoconus and corneal granular dystrophy and the second son has keratoconus alone. The keratoconus in this family is thought to be an autosomal dominant or an X-linked inheritance pattern. Granular dystrophy is an autosomal dominant inheritance. This familial case suggests that the gen...

Objectives Comparison of topography and corneal higher order aberrations (HOA) data of fellow normal eyes of unilateral keratoconus patients with keratoconus eyes and control group. Materials and Methods The records of 196 patients with keratoconus were reviewed. Twenty patients were identified as unilateral keratoconus. The best corrected visual acuity (BCVA), topography and aberration data ...

Introduction: There are many reports on the association of various psychiatric disorders with visual impairment. The dry eye syndrome depressive has been particularly well documented. In context keratoconus patients group, data similar relationships inconclusive. Attempts have also made to assess personality suffering from keratoconus, and first study in this area was produced as early 1976. Ma...

K eratoconus (OMIM148300) is a bilateral, non-inflammatory, slowly progressive, corneal ectasia that is a major cause of corneal transplant. Characteristically, the cornea becomes thin and conical, with myopia and irregular astigmatism that leads to vision impairment. The incidence of keratoconus is between 50 and 230 per 100 000, with remarkable differences between ethnic groups. Although the ...

BACKGROUND Keratoconus is a noninflammatory disease characterized by thinning and scarring of the central portion of the cornea. The etiology is unclear. In this study, we sought to identify mRNAs that are differentially expressed in the stroma of keratoconus corneas in comparison to those of corneas from normal individuals and patients with other corneal diseases. MATERIALS AND METHODS Total...

A male medical student, aged 22, had bilateral keratoconus which had been successfully treated by Mr. H. Treissman with contact lenses for 7 years. Recently the left eye had become intolerant to the contact glass with recurrent corneal ulceration and scar formation. The patient was referred to Mr. B. W. Rycroft for consideration of keratoplasty. History.-There were no points of relevant ophthal...

PURPOSE To survey the standard keratoconus grading scale (Pentacam®-derived Amsler-Krumeich stages) compared to corneal irregularity indices and best spectacle-corrected distance visual acuity (CDVA). PATIENTS AND METHODS Two-hundred and twelve keratoconus cases were evaluated for keratoconus grading, anterior surface irregularity indices (measured by Pentacam imaging), and subjective refract...

WHY EARLY DIAGNOSIS? In corneal refractive surgery, early diagnosis of keratoconus (subclinical asymptomatic keratoconus) is of great importance in patients seeking surgery because it can prevent progression of the pathology after surgery and make it symptomatic (corneal ectasia), thus creating the need for diagnostic tests that provide high sensitivity (ability to detect the disease in affecte...

PURPOSE To evaluate corneal cell morphology in patients with keratoconus using an in vivo slit scanning confocal microscope. METHODS A cross-sectional study was conducted to evaluate the corneal cell morphology of 47 keratoconus patients and 32 healthy eyes without any ocular disease. New keratoconus patients with different disease severities and without any other ocular co-morbidity were rec...