Disturbed fluid flow or modulated shear stress is associated with vascular conditions such as atherosclerosis, thrombosis, and aneurysm. In vitro simulation of the fluid flow around the plaque micro-environment remains a challenging approach. Currently available models have limitations such as complications in protocols, high cost, incompetence of co-culture and not being suitable for massive e...

BACKGROUND AND OBJECTIVES Storage lesions may prevent transfused platelets to respond to agonists and arrest bleeding. The aim of this study was to evaluate and quantify the capacity of platelet activation during storage using flow cytometry and new markers of platelet activation. MATERIALS AND METHODS Activation responses of platelets prepared by apheresis were measured on days 1, 5, 7 and 1...

PURPOSE To test our hypothesis about whether there is water migration in the horizontal corneal plane and investigate its developmental mechanism. METHODS A fluorescein solution was intrastromally injected into normal and edematous corneas of rabbits, and the movement of the fluorescein solution was observed and recorded over time. RESULTS In normal corneas, the water flow was characterized...

A comparative performance analysis of the CFD platforms OpenFOAM and FLOW-3D is presented, focusing on a 3D swirling turbulent flow: a steady hydraulic jump at low Reynolds number. Turbulence is treated using RANS approach RNG k-ε. A Volume Of Fluid (VOF) method is used to track the airewater interface, consequently aeration is modeled using an EulerianeEulerian approach. Structured meshes of c...

A high-speed gas flow, generated by a miniature supersonic nozzle for microparticle acceleration, is investigated. In medical application, the powder formulation of drugs can be delivered into human skin or mucosal tissue for the treatment of a range of diseases. One of the main concerns for designing and evaluating such system is ensuing that microparticles are delivered into human skin with a...

We present experimental results on the analysis of turbulent velocity measurements in the flow that develops in the gap between two coaxial counter-rotating disks (von K£rm£n swirling flow). In the absence of a well-defined mean velocity we introduce the use of a "local Taylor hypothesis" to obtain spatial information from hot-wire measurement at a fixed location. The results are in agreement w...

Swirling flows are related to the spiral motion in the tangential direction in addition to the axial and radial direction using several swirl generators. These type of flows are used in combustion chambers to improve flame stability, heat exchanger to enhance heat transfer coefficients, agricultural spraying machines and some vertical pipes to move slurries or transport of materials. However, o...