Cystic fibrosis transmembrane conductance regulator (CFTR), known as an epithelial Cl− channel, is increasingly noted to be expressed in the nervous system, although whether and how it plays a role neuronal excitability unclear. Given association of CFTR with fertility, we tested here possible involvement regulating hypothalamic neuron excitability. Patch-clamp Ca2+ imaging showed that pharmaco...

Ectonucleotide pyrophosphatase/phosphodiestrase 2 (Enpp2) isolated from the supernatant of human melanoma cells is a lysophospholipase D that transforms lysophosphatidylcholine into lysophospatidic acid. Although multiple analyses have investigated the function of Enpp2 in the hypothalamus, its role in the uterus during the estrous cycle is not well understood. In the present study, rat uterine...

In rodents, the display of sexual behavior during proestrus-estrus transition depends on the effect of estradiol and progesterone. Progesterone exerts its effects through intracellular receptor (PR) of which two isoforms (PR-A and PR-B) are found, with different regulation and function. In this study the effects of mating on the expression pattern of PR isoforms in the hypothalamus were investi...

A total of 191 crossbred sows were used to determine the effect of energy intake during one lactation on (1) sow and pig performance and (2) the percentage of sows in estrus by 7, 14, 21 and 70 d postweaning. Sows received 8 (Lo) or 16 (Hi) Mcal of metabolizable energy (ME)/d (Exp. 1 and 2) and 8 (Lo), 12 (Md) or 16 (Hi) Mcal of Me/d (Exp. 3) during a 28-d lactation period. All sows were fed an...

Human chorionic gonadotropin (hCG) may boost progesterone production and attenuate maternal-immune response against concepti in ewes, increasing prenatal survival. The present study examined effects of repeated hCG administration after mating on serum progesterone concentration and complete blood counts (CBC) during early gestation, as well as offspring numbers at parturition. Fifty-six ewes we...

The present experiment was designed for estrus induction in post-partum anestrus cattle. A total of 120 cows were examined reproductive status, and 30 incorporated induction, including 24 6 normal cyclic cows. assigned to 5 groups (6 animals per group). group-1 induced using Ovsynch protocol, while group-2 inserted TRIU-B (958 mg progesterone) intra-vaginal inseminated at a fixed time. group-3 ...

The present study was designed to investigate the impact of exogenous administration of GnRH (Receptal VET®, Intervet Pharmaceuticals Ltd., India) on serum progesterone profile and conception rates during mid luteal phase of estrous cycle in buffaloes. Estrus was induced using Cyclix 2 mL. i/m. (Intervet India Pvt. Ltd., India) and animals were bred naturally during observed estrus. The buffalo...

Small, J. A., Charmley, E., Rodd, A. V. and Fredeen, A. H. 1997. Serum mineral concentrations in relation to estrus and conception in beef heifers and cows fed conserved forage. Can. J. Anim. Sci. 77: 55–62. A study was undertaken to examine serum mineral concentrations in relation to estrus and first service conception (FSC) in beef cattle fed conserved forage. Blood samples were taken from ye...

Thirty-nine multiparous ewes (19 Pelibuey and 20 Romanov × Pelibuey) treated with fluorogestone acetate impregnated intravaginal sponges were used to evaluate the effects of low pregnant mare serum gonadotropin (PMSG) doses and genotype on their reproductive efficiency under heat stress conditions. The sponge treatment lasted for 12 days, and 24 h before sponge removal, ewes of each genotype we...

A trial was conducted to evaluate the ability of a prostaglandin analog, Luprostiol (LP), to synchronize estrus in Brahman cows and heifers. Animals were injected with either 0, 3.75, 7.5, 15 or 30 mg LP or 500 micrograms cloprostenol (CLP) on d 8 or 9 after estrus (d 0). All concentrations of LP (greater than 0 mg) and CLP caused luteolysis in cows and heifers, as indicated by a decline (P les...