The successful surgical treatment of medically refractory epilepsy is based on one of three different principles: (1) elimination of the epileptic focus, (2) interruption of the pathways of neural propagation, and (3) increasing the seizure threshold through cerebral lesions or electrical stimulation. Temporal lobe epilepsy, being the most common focal epilepsy, may ultimately require temporal ...

OBJECT Dose-volume data concerning the brainstem in stereotactic radiosurgery (SRS) for trigeminal neuralgia (TN) were analyzed in relation to associated complications. The authors present their set of data and compare it with currently cited information on brainstem dose tolerance associated with conventional fractionated radiation therapy and hypofractionated radiation treatment of other dise...

PURPOSE To systematically review the evidence for the radiotherapeutic and surgical management of patients newly diagnosed with intraparenchymal brain metastases. METHODS AND MATERIALS Key clinical questions to be addressed in this evidence-based Guideline were identified. Fully published randomized controlled trials dealing with the management of newly diagnosed intraparenchymal brain metast...

Purpose: To present the value of radiosurgery in oculoplastic procedures. Methods: My experience of 3 years and approximately 1000 oculoplastic procedures using radiosurgery was synthesized. The radiosurgical techniques that I have found useful are presented. Conclusions: Radiosurgery is an excellent surgical tool for performing oculoplastic procedures because it coagulates blood vessels as it ...

We report five cases of symptomatic delayed cyst formation after radiosurgery for intracranial arterial venous malformations. Median time to discovery of the cysts following most recent radiosurgery was 59 months (range, 34-89 months). In all five patients, the radiation therapy-induced cysts exhibited tumefactive characteristics, including vasogenic edema, mass effect, and nodular enhancement....

Stereotactic radiosurgery undoubtedly represents an important therapeutic procedure for various intracranial pathologies, especially tumours, although they are not entirely complication-free. Radiosurgery have been considered a good management strategy for the majority of small-to-medium size vestibular schwannomas. The authors describe a case of high-grade glioma associated with a previous rad...

PURPOSE To determine whether pre-treatment growth rate of vestibular schwannomas (VS) predict response to radiosurgery. METHODS A retrospective review of a prospectively maintained database of all VS patients treated with 12Gy prescription dose between September 2005 and June 2011 at our institution using the Leksell Model 4C Gamma Knife Unit was conducted. Patients who had a minimum of 12-mo...

BACKGROUND AND PURPOSE Gamma knife radiosurgery is an alternative for the treatment of medically refractory trigeminal neuralgia. Few reports of posttreatment MR imaging appearance of cranial nerve V exist. Our purpose was to define MR imaging characteristics in cranial nerve V after gamma knife radiosurgery. METHODS We retrospectively reviewed MR images of 15 patients who underwent gamma kni...

OBJECTIVES Although radiosurgery has been found to be a safe and effective alternative treatment, seizure outcome of arteriovenous malformation (AVM) radiosurgery has not been documented in detail. We report the effect of Gamma Knife radiosurgery (GKRS) on seizures associated with AVMs and discuss the various factors that influence the prognosis. MATERIAL AND METHODS Between 1992 and 2004, 24...

OBJECTIVE To report an unusual case of malignant degeneration in a ganglioneuroma of the jugular foramen post stereotactic radiosurgery as well as to systematically review the pertinent literature involving radiosurgery associated malignancies. BACKGROUND Ganglioneuromas are uncommon lesions of the peripheral nervous system and infrequently reported in the head and neck region. There have bee...