Pharmacokinetic (PK) studies of radiopharmaceuticals (RPs) are distinctive because small concentrations active ingredients. Whereas methods applicable to non-RP medicinal products cannot be used for RPs, radionuclide can provide an insight into behaviour. The aim the study was compare approaches pre-clinical PK evaluation RPs and other products. article describes main aspects non-RPs, defining ...

pet (positron emission tomography) is a powerful imaging technique that can provide quantitative information on the distribution of positron emitter labeled radiopharmaceuticals (pet radiopharmaceuticals) in the body. positrons (ß+) are positively charged beta particles. they are emitted when the atom is proton rich. a positron has only a transient existence. after losing all of its kinetic ene...

Objective: Radiopharmacy is a special field of pharmacy that examines, develops, conducts quality controls, deals with distribution and application pharmaceutical forms called radiopharmaceuticals are used for diagnostic therapeutic purposes, carrying radioactive properties together. Radiopharmaceuticals contain radionuclides. This the most important difference distinguishes from other conventi...