OBJECTIVES Evaluate relationships between MRI and clinical/laboratory/radiographic findings in rheumatoid arthritis (RA). METHODS 637 methotrexate-naive patients (GO-BEFORE) and 444 patients with active RA despite methotrexate (GO-FORWARD) were randomly assigned to subcutaneous placebo + methotrexate, golimumab 100mg + placebo, golimumab 50mg + methotrexate, or golimumab 100mg + methotrexate ...

Radiographic changes of rickets are well characterized, but no method of grading the severity of these changes has been in general use. Consequently, it is difficult to compare objectively or follow radiographic improvement. We prospectively evaluated the utility and reproducibility of a scoring method for measuring the severity of rickets. A 10-point score for radiographs of wrists and knees w...

Radiographic progression is an important outcome measure in clinical trials and observational studies with patients with rheuamtoid arthritis. In this article we describe several aspects of measuring radiographic progression. We introduce the scoring method, discuss scoring methodology and issues regarding reliability of scoring, describe the relation between disease activity, radiographic prog...

A method for quantitative measurement of gas volume changes in upper airway is presented in this paper. The aim of this study is to assess the feasibility of a novel Cone Beam Computerized Tomography (CBCT) technique for quantitative measurement of gas volume in upper airway. Our application is defining and tracking minute volume changes (a few milliliters) of airways caused by surgery, such as...

objectives : optimum viewing conditions facilitate identification of radiographic details and decrease the need for retakes, patients’ costs and radiation dose. this study sought to evaluate the effects of different viewing conditions on radiographic interpretation. materials and methods: this diagnostic study was performed by evaluating radiograph of a 7mm-thick aluminum block, in which 10 hol...