as recent advancements in biology shows, the molecular machines specially proteins, rna and complex molecules play the main role of the so called cell functionality. it means a very big part of the system biology is concerned with the interactions of such molecular components. drug industries and research institutes are trying hard to better understand the concepts underlying these interactions...

The idea to hold an international conference on radiation and health arose as a natural response to the mounting evidence of serious health effects on populations resulting from the Chernobyl accident. The nature of the Chernobyl accident, where large amounts of radioactive nuclides spread in the reactor area and all over Europe, dictated the emphasis of the presented papers covering both direc...

 Background: To analyze the dosimetric and radio biologic advantages between intensity modulated radiotherapy (IMRT) and 3 dimensional conformal radiotherapy (3DCRT) and selection of optimal photon energy for IMRT treatments. Material and methods: 24 patients with localized prostate carcinoma were planned for 3DCRT and IMRT techniques. Radiation dose of 54 Gy with 2 Gy/fraction, was planned to ...

Abstract Background Although the classic radiobiologic principles of radiotherapy are well understood, unique effects large fractional does that characterize stereotactic (SRT), specifically in terms antitumor immune cellular processes, vascular damage, tumor necrosis, and apoptosis on brain metastasis have yet to be adequately demonstrated. The objective this study is provide first in-human ev...

background: to analyze the dosimetric and radio biologic advantages between intensity modulated radiotherapy (imrt) and 3 dimensional conformal radiotherapy (3dcrt) and selection of optimal photon energy for imrt treatments. material and methods: 24 patients with localized prostate carcinoma were planned for 3dcrt and imrt techniques. radiation dose of 54 gy with 2 gy/fraction, was planned to p...

Background. Delays in initiation and interruptions the radiotherapeutic management of head neck malignancies have radiobiologic implications allowing for accelerated repopulation surviving tumor cells. This phenomenon has been demonstrated to translate into poorer survival outcomes control, typically manifesting as progression that may require a new radiotherapy set-up. Such adjustments are acc...

in this paper, we present a multi-formalism modeling framework (abbreviated by mfmf) for modeling and simulation. the proposed framework is defined based on the concepts of meta-models and uses object-orientation to overcome the complexities and to enhance the extensibility. the framework can be used as a basis for modeling by various formalisms and to support model composition in a unified man...