We have previously shown that abnormal iron metabolism might be one underlying mechanism of the renal damage observed in the angiotensin II-infused rat. Transforming growth factor-beta1 (TGF-beta1) is known to play a crucial role in the development of renal damage induced by activation of the renin-angiotensin-aldosterone system. The purpose of the present study was to examine the effects of an...

objective: previous studies showed that grape seed extract (gse) is an excellent natural substance with potent antioxidant effect and free radical scavenger. this study aimed to evaluate the effect of gse on motor dysfunctions and thalamic local electroencephalography (eeg) frequency bands' powers in rats with parkinson's disease (pd). materials and methods: in this study 8 µg 6-hydro...

Oxygen-derived free radical formation can lead to cellular injury and death. Under normal situations, the human body has a free radical scavenger system (catalase, superoxide dismutase) that can detoxify free radicals. Antioxidant vitamins and enzymatic and synthetic oxygen-derived free radical scavengers have been used clinically to prevent the formation of oxidized LDL and to prevent reperfus...

The aim of the present study was to evaluate the effect of troxerutin (TXN) on Nickel (Ni) toxicity by using rats and in vitro model. Ni toxicity induced in male albino wistar rats (20 mg/kg body weight (b.w) was administered orally for 20 days). TXN was administered orally (100 mg/kg (b.w) for 20 days with administration of Ni. The toxic effect of Ni and the action of TXN was measure by determ...

introduction: humic acids have adverse effects on the water quality, then should be removed from water resources. the aim of this study was to evaluate the effect of nitrate as a radical scavenger for removal of humic acid from aqueous solutions by electron beam irradiation. materials and methods: in this study, after preparation of stock humic acid solution in alkaline condition, different con...