BACKGROUND Radiation therapy (RT) including tomotherapy has been widely used to treat primary tumors, as well as to alleviate the symptoms of metastatic cancers. OBJECTIVE The primary purpose of this study was to examine the characteristics of the clinical features and pathophysiological mechanisms associated with acute radiation dermatitis in cancer patients that received tomotherapy, and co...

Background: Acute radiation dermatitis is a very common side effect of radiation therapy in large numbers of cancers including breast cancer. Despite high prevalence rate of acute radiation dermatitis and also wet desquamation, a few trials on prophylaxis of this complication using topical treatment have been conducted. Despite effectiveness of topical corticosteroids in treatment of acute radi...

Radiation therapy (RT) is associated with high incidence of dermatologic adverse events. dermatitis a major cutaneous side effect RT. The article presents current views on pathogenesis radiation and modern approaches to prophylaxis treatment this reaction.

BACKGROUND This two-arm, randomized clinical study aimed to compare efficacy between topical Alpha ointment and topical hydrocortisone cream (1%) in the healing of radiation-induced dermatitis in breast cancer patients. METHODS The inclusion criteria comprised newly pathologically proven, locally advanced breast cancer (treated with modified radical mastectomy followed by sequential adjuvant ...

To the Editor: Radiation recall dermatitis is a phenomenon seen in patients who have received radiation therapy followed by chemotherapy. Tamoxifen, a selective estrogen receptor (ER) modulator, has been implicated in three cases of radiation recall dermatitis (1–3). We report a fourth case, which we believe to be the first reaction documented in the United States. An 88-year-old woman was diag...

BACKGROUND AND OBJECTIVES Radiation dermatitis occurs in a majority of patients with breast cancer who receive radiation therapy (RT), causes significant pain, and may necessitate treatment delay. Light emitting diode (LED) photomodulation has been reported to minimize radiation dermatitis. This study sought to further evaluate the efficacy of LED photomodulation in lessening radiation dermatit...

Radiation therapy used alone or in combination with chemotherapy and/or surgery for the treatment of cancer can be extremely problematic and painful to the patient. The adverse effects of radiation therapy include dryness, itching, peeling, or blistering of the skin. There are numerous formulas and compounds that can be utilized to help patients with radiation burns. The compounding pharmacist,...