Background: Sildenafil (Viagra) has been introduced to treat erectile dysfunction by acting as phosphodiesterase 5 inhibitor and hence accumulation of guanosine cyclic monophosphate (cGMP). On the other hands, the nitric oxide/cGMP signaling pathway has crucial role in synaptic plasticity processes like long-term potentiation (LTP) in the central nervous system considered as a model of learning...

background:  the purpose of this study was to report the preoperative complaints and postoperative outcome of patients after removal of the radial head prosthesis.   methods:  this is a retrospective review of 14 adult patients (6 females and 8 males) from 2007 to 2011, who underwent radial head prosthesis removal by three surgeons. the average time between implantation and removal was 23 month...

One method to deal with the problem of soft soil is accelerate consolidation by preloading and prefabricating a vertical drain (PVD). Consolidation analysis was based on one-dimensional theory that required PVD as an equivalent circular well. Further studies simple approximate for consolidated were represented permeability coefficients, kve. The conductivity coefficient influenced coefficients....

geotechnical investigations of waste fills are rarely undertaken, and consequently the geotechnical community has little knowledge of their engineering properties. in this study, a geotechnical testing program was conducted to evaluate the engineering properties of old municipal solid waste sampled in whamyung msw landfill site, busan, korea. the conducted tests included water content, specific...

The present study was designed to evaluate the learning and memory, in an altered physiological state associated with increased blood pressure and activated renin angiotensin system in Wistar rats. The role of angiotensin in cognitive function was assessed by treatment with angiotensin converting enzyme (ACE) inhibitor enalapril (2 mg/kg), angiotensin 1 receptor (AT(1)) antagonist losartan (5 m...

growing evidence suggests that serotonin plays an important role in learning and memory and all its receptors might be implicated in this process. the present study aimed at investigating and comparing the possible involvement of 5-ht 3 and 5-ht 4 receptor (r) agonists/antagonists upon consolidation of inhibitory avoidance memory in the pre-limbic (pl) area. bilateral intra-pl microinjections o...

BACKGROUND Up to 30% of patients suffer from long-term functional restrictions following conservative treatment of distal radius fractures. Whether duration of cast immobilisation influences functional outcome remains unclear. METHODS/DESIGN The aim of the study is to evaluate whether the duration of immobilization of non or minimally displaced distal radial fractures can be safely reduced. W...

background: the present study was designed to ascertain serial changes on distal radius radiographic parameters attributable to aging.       methods: in this prospective study, the sample consisted of 120 healthy individuals who were divided into four age groups each containing 15 males and 15 females. in the two below-20-year-old groups, only ulnar variance could be investigated. wrist radiogr...

 Abstract Bronchoalveolar carcinoma presenting as non-resolving consolidation is an uncommon presentation. The typical presentation of bronchoalveolar carcinoma is asymptomatic (solitary nodule) and remains without symptoms even as disease disseminates. We report a case of bronchoalveolar carcinoma presenting as non-resolving consolidation in a young male with productive cough, exertional ...