نتایج جستجو برای: r13

تعداد نتایج: 224  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Nancy D Doolittle Lauren E Abrey W Archie Bleyer Steven Brem Thomas P Davis Paula Dore-Duffy Lester R Drewes Walter A Hall John M Hoffman Agnieszka Korfel Robert Martuza Leslie L Muldoon David Peereboom Darryl R Peterson Samuel D Rabkin Quentin Smith Glen H J Stevens Edward A Neuwelt

The blood-brain barrier (BBB) presents a major obstacle to the treatment of malignant brain tumors and other central nervous system (CNS) diseases. For this reason, a meeting partially funded by an NIH R13 grant was convened to discuss recent advances and future directions in translational research in neuro-oncology and the BBB. Cell biology and transport across the BBB, delivery of agents to t...

Journal: :Curationis 1993
L R Uys

Student w astage during basic nursing programmes has been estimated at between 20% and 47% per annum over the last 10 years (Kotze, 1987; SANA. 1983). The training of every student costs the state approximately R13 500 per annum according to an investigation done by the SA Nursing Association in 1987. The economic loss due to the student wastage is therefore significant. At the same time studen...

Journal: :The journal of physical chemistry. A 2013
Chong-Wen Zhou Jorge Mendes Henry J Curran

The temperature and pressure dependence of the addition reaction of ethyl methyl ketone (EMK) with HO2 radical has been calculated using the master equation method employing conventional transition state theory estimates for the microcanonical rate coefficients in the temperature range of 600-1600 K. Geometries, frequencies, and hindrance potentials were obtained at the B3LYP/6-311G(d,p) level ...

2011
Tomoya Mori Masahisa Fujita Marcus Berliant

Literature from several phases of the career of Masahisa Fujita is surveyed chronologically, with a view toward future contributions in these areas. First we address the economic structure of the interior of a city with mobile consumers, adding production. Next we provide a critical discussion of the New Economic Geography, in particular distinguishing between recent approaches employing two re...

2015
Kazuhiro Yamamoto

A two-region model is proposed in this paper. Manufactured goods can be produced with cottage technology under constant returns to scale or with modern technology using differentiated intermediate goods, which are produced with increasing returns to scale technology. In the model, there may be multiple equilibria, and, in such cases, the initial conditions determine the equilibrium that the eco...

2004
Pierre M. Picard Dao-Zhi Zeng

In many developing countries, agriculture hires at least as many workers as manufacturing industries. We investigate an economic geography model in which agricultural goods are costly to transport and in which manufactures hire labor from the local agricultural sector as unskilled labor. Our conclusions show that the parameters in the agricultural sector are crucial to determine the spatial con...

1995
Oliver Kirchkamp

We apply the idea of evolution to a spatial model. Prisoners’ dilemmas or coordination games are played repeatedly within neighbourhoods where players do not optimise but instead copy successful strategies. Discriminative behaviour of players is introduced representing strategies as small automata, which can be in different states against different neighbours. Extensive simulations show that co...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2002
Nancy D Doolittle Lauren E Abrey Nicolay Ferrari Walter A Hall Edward R Laws Roger E McLendon Leslie L Muldoon David Peereboom Darryl R Peterson C Patrick Reynolds Peter Senter Edward A Neuwelt

The November 2000 NIH report of the Brain Tumor Progress Review Group identified delivering and targeting therapeutic agents as a priority in the treatment of malignant brain tumors. For this reason, the seventh annual Blood-Brain Barrier Disruption Consortium meeting, partially funded by an NIH R13 Grant, focused on recent advances in targeted delivery to the central nervous system, clinical t...

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