N,N-didecyl-N-methyl-poly(oxyethyl) ammonium propionate is a quaternary ammonium compound that is used to disinfect medical devices. Occupational allergic contact dermatitis caused by quaternary ammonium compounds in healthcare workers is an increasingly important issue (1). We report a case of severe allergic contact dermatitis caused by N,N-didecyl-N-methyl-poly(oxyethyl) ammonium propionate ...

The layered trirutile phases HMWO6 (M = Nb, Ta) and the layered perovskite H2W2O7 (synthesized by acid leaching of Bi2W2O9) were exfoliated into nanoscale colloids by reaction with quaternary ammonium hydroxides.

the acute intravenous toxicities of a selection of three potential long-acting local anaesthetics belonging to the series of2- phenoxyethyldialkylamine were determined in mice. two of the compounds were tertiary amines and the third a quaternary ammonium derivative.the i.v. median lethal dose, (ldso) of one of the tertiary compounds, 21a [n, n- diethyl-2- (2,6- diisopropyl) ethyl amine hydrochl...

The progress of antimicrobial therapy contributes to the development of strains of fungi resistant to antimicrobial drugs. Since cationic surfactants have been described as good antifungals, we present a SAR study of a novel homologous series of 140 bis-quaternary imidazolium chlorides and analyze them with respect to their biological activity against Candida albicans as one of the major opport...

In the title compound, C(19)H(26)O(2), the A ring adopts a chair conformation, whereas the B and C rings both adopt distorted half-chair conformations with the quaternary C atom common to both rings lying 0.577 (3) and 0.648 (3) Å out of the approximate plane defined by the remaining five C atoms (r.m.s. deviations = 0.1386 and 0.1156 Å) for the B and C rings, respectively. Mol-ecules are assem...

We use Quaternary stratigraphy to reconstruct landscape evolution and measure tectonic deformation of the Olympic Mountains section of the Pacifi c Northwest Coast Range. An important motivation for understanding orogenesis here, and throughout the Coast Range, is the concern about the relationship of active deformation to seismic hazards associated with the Cascadia subduction zone. There is a...

A dianionic Ireland-Claisen rearrangement of chiral, nonracemic α-methyl-β-hydroxy allylic esters has been developed that proceeds with high diastereoselectivity and provides products containing three contiguous stereogenic carbons, including a quaternary center. The potential utility of the rearrangement for complex molecule synthesis is also demonstrated.

Depending on the spacing of their positive charges, ionenes, a class of quaternary ammonium polymers, increased the interferon-inducing activity of poly(inosinic acid).poly(cytidylic acid) in mouse L-929 cells, whereas they did not enhance poly(inosinic acid).poly(cytidylic acid) induced interferon production in primary rabbit kidney and human skin fibrolast cells.

Shedlovsky's results,16 which differ from all others. There can be no doubt that most if not all, of these minima are spurious. One observation, which we have made may have an important bearing on this problem. In many cases, on addition of the first sample, the resistance of the solution drifted to lower values. The rate of this drift depended on the salt as well. as on the sample. In some ins...

A silicogermanate, PKU-12, with the -CLO type of zeolite framework was hydrothermally synthesized under fluoride media using diisopropylethylmethylammonium as a structure directing agent. The formation of the silicogermanate zeolite with 20-ring channels has not only extended the -CLO family from phosphates into silicogermanates, but also demonstrated its structural diversity.