BACKGROUND Recent molecular biological investigations have identified abnormal genes in familial forms of long QT syndrome, but in bradycardia dependent acquired long QT syndrome, no such genetic abnormality has yet been identified. OBJECTIVE To investigate the relation between the responses of QT interval to pacing change and to disopyramide. METHODS This study included 13 patients with br...

The correct measurement of the QT interval (using correction formulas, preferably Fridericia and Framingham) as well a interpretation causes clinical consequences prolongation is very important in practice. Drug-induced long syndrome (DILQTS) one most common LQTS. In diagnosis management DILQTS, it can be useful to follow three-step rule presented this article: detailed pharmacological anamnesi...

BACKGROUND AND PURPOSE We studied the relationship of heart rate-corrected QT interval with subclinical atherosclerosis, as determined by ultrasonographic measurement of carotid intima-media thickness (IMT) in nondiabetic subjects in the Insulin Resistance Atherosclerosis Study (IRAS). Prolonged heart rate-corrected QT interval is an unfavorable prognostic factor of cardiovascular morbidity and...