MicroRNAs (miRNAs) are endogenous, non-coding, small RNAs, which play a critical role in regulating varieties of the biological and pathologic processes. Several reports have indicated that miR-370 acts as a tumor suppressor in varieties of tumors. However, the roles of miR-370 in osteosarcoma have not been reported. In this study, our objective was to explore the biological functions and its m...

" atrophy of the skeletal muscles from congenital defect and subsequent pathological change, unassociated with any lesion of the nervous system, and characterised by progressive muscular wasting" and weakness during infancy and childhood."(l) The patient, a young Wazir Pathan, aged about 8, was brought to hospital with the history of 4 years' difficulty in walking, with frequent falls when walk...

Anzar Mahmood 1, Faisal Baig 1, Nabil Alrajeh 2, Umar Qasim 3, Zahoor Ali Khan 4,5 and Nadeem Javaid 1,* 1 COMSATS Institute of Information Technology, Islamabad 44000, Pakistan; [email protected] (A.M.); [email protected] (F.B.) 2 College of Applied Medical Sciences, Department of Biomedical Technology, King Saud University, Riyadh 11633, Saudi Arabia; [email protected] 3 Cameron Lib...

MicroRNA (miR)-370 functions as a tumor suppressor or promoter in several cancers. However, the expression and biological role of miR-370 in colon cancer remains undefined. In the present study, miR-370 expression in both normal and malignant colon tissues was quantified by quantitative polymerase chain reaction. An in vitro cell viability and apoptosis assay and an in vitro xenograft tumor mod...

Production and Physicochemical Characteristics.................................. 368 Rabbits.................................................................. 368 Guinea pigs............................................................... 369 Mice................................................................... 369 Rats................................................................... 370 Pou...

synesthesia is an extended  type of poetic image through transferring five  natural senses of human from a sense to another which poet creates by expanding his imagination and producing and influencing images on the audience. the  present study has investigated synesthesia in poems of abol qasem ahshabi and sohrab sepehri since this phenomenon influences and  attracts audience's attention ...

Policy Perspectives interviewed four senior experts on Afghanistan to understand the current state of affairs regarding and Pakistan-Afghanistan relations in broader perspective history, ideology, culture. The included former ambassador Pakistan Vice Chairman Institute Studies (IPS), Islamabad, Syed Abrar Hussain; Director, Study Center, University Peshawar, Professor Dr Fakhr-ul-Islam; Directo...