Aggregation induced emission based delayed fluorescence from assembly of gold clusters for sensing pyrophosphate.

Retrospective observational analysis of ferric pyrophosphate citrate (triferic®) administered via dialysate. Experience at a single facility over 2 years

The conversion of geranyl pyrophosphate to (-)-endo-fenchol is considered to proceed by the initial isomerization of the substrate to (-)-(3R)-linalyl pyrophosphate and the subsequent cyclization of this bound intermediate. Incubation of (1R)-[2-14C,1-3H]- and (1S)-[2-14C,1-3H]geranyl pyrophosphate with a preparation of (-)-endo-fenchol cyclase (synthase) from common fennel (Foeniculum vulgare)...

Syntrophus gentianae is a strictly anaerobic bacterium which ferments benzoate to acetate, CO2 and H2 in the presence of hydrogen-utilizing partner bacteria. Benzoate is activated by a benzoyl CoA ligase enzyme which forms AMP and pyrophosphate as coproducts. Pyrophosphatase activity was found to be largely membrane bound. Pyrophosphate hydrolysis was associated with proton translocation across...

Octaprenyl pyrophosphate synthase (OPPs) is involved in the synthesis of the side chains of ubiquinone and menaquinone and catalyzes consecutive condensation reactions of farnesyl pyrophosphate with isopentenyl pyrophosphate to generate polyprenyl pyrophosphate and pyrophosphate. In order to investigate the roles played by OPPs in the metabolism of ubiquinone and menaquinone and the enzymatic m...

In the work it is shown by spectrophotometry method that depending on concentration ratio of ligands [PPi4–]/[Cit3–] in pyrophosphate-citrate electrolyte, cobalt (II) ions form not only citrate [Co(Cit)2]4– and pyrophosphate [Co(PPi)2]6–, but also polyligand complexes [Co(PPi)m(Cit)n]+2–(4m+3n). The composition [Co(PPi)Cit]5– was determined, equilibrium constant reaction their formation stabili...

Vitamin B1 is nearly exclusively present in animal tissues as aneurin pyrophosphate (Ochoa and Peters, 1938). The vitamin is first converted to aneurin pyrophosphate by the tissues and in this form it enables the oxidative decarboxylation of pyruvic acid to take place allowing glucose metabolism to go beyond the pyruvate stage (Banga, Ochoa, and Peters, 1939). It has been shown more recently th...

Pyrophosphate linkages have a number of important roles in biology and are also formed chemically with great ease. They often are unwanted products, such as in the nonenzymatic oligomerization of mononucleotides. We have found that Zr(4+)- and Th(4+)-ions catalyze the symmetrical hydrolysis of pyrophosphate linkages. Oligonucleotide analogs linked by pyrophosphate bonds are substantially degrad...

A commercial pyrophosphatase from Saccharomyces cerevisiae selectively hydrolyzed sodium pyrophosphate, but showed no significant activity towards a range of other organic and condensed inorganic phosphorus compounds. Pyrophosphate determined by pyrophosphatase hydrolysis accounted for 38 12% (mean standard error of 19 sites) of the non-reactive phosphorus in soil solution obtained by centrifug...

UNLABELLED Farnesyl pyrophosphate synthase (FPS; EC 2.5.1.10) is a key enzyme in isoprenoid biosynthetic pathway and provides precursors for the biosynthesis of various pharmaceutically important metabolites. It catalyzes head to tail condensation of two isopentenyl pyrophosphate molecules with dimethylallyl pyrophosphate to form C15 compound farnesyl pyrophosphate. Recent studies have confirme...