نتایج جستجو برای: pyrimidinones
تعداد نتایج: 113 فیلتر نتایج به سال:
Supramolecular polymers can substantially influence the dynamic mechanical properties in slightly crosslinked polymer networks. One prominent example of supramolecular building blocks is 2-ureido-4[1H]-pyrimidinones (UPy). Combining UPy-terminated segments with classical covalent-reactive monomers implements behavior photopolymerizable systems. In this work, a UPy-based methacrylic monomer (up ...
Heterocyclic scaffold has been under discovery due to their considerable therapeutic and medicinal importance. One of such heterocycles 2-pyrimidinone, while not naturally occurring, are receiving increased attention because of their wide-ranging biological activity like, an efficient inhibitor of DNA synthesis in E. coli, inhibitors of the enzyme cytidinedeaminase, and as metaphase inhibitors....
Plasmodium falciparum, the Apicomplexan parasite that is responsible for the most lethal forms of human malaria, is exposed to radically different environments and stress factors during its complex lifecycle. In any organism, Hsp70 chaperones are typically associated with tolerance to stress. We therefore reasoned that inhibition of P. falciparum Hsp70 chaperones would adversely affect parasite...
In the title compound, C(20)H(21)N(5)O(4), the ring system containing the three fused rings is essentially planar (r.m.s. deviation for all 12 non-H atoms = 0.041 Å). The phenyl ring makes a dihedral angle of 54.41 (6)° with this ring system. The isopropyl group is disordered over two positions, with site-occupancy factors of 0.753 (9) and 0.247 (9). The structure is mainly stabilized by weak i...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید