نتایج جستجو برای: pyridinyl
تعداد نتایج: 490 فیلتر نتایج به سال:
DESCRIPTION The active ingredient in PROTONIX (pantoprazole sodium) Delayed-Release Tablets and PROTONIX (pantoprazole sodium) For Delayed-Release Oral Suspension is a substituted benzimidazole, sodium 5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl] sulfinyl]1H-benzimidazole sesquihydrate, a compound that inhibits gastric acid secretion. Its empirical formula is C16H14F2N3NaO4S x 1.5...
In the pair of helical conformational polymorphs of the coordination polymer {[AgL](CF3SO3)}infinity(L=2-pyridinyl-3-pyridinylmethanone), the 2(1) helices of opposite chirality in one supramolecular isomer are stacked alternately to form a racemate, while the 4(1) helices in the other are assembled homochirally by inter-chain argentophilic interaction to generate a conglomerate.
In human cancers, loss of PTEN, stabilization of hypoxia inducible factor-1a, and activation of Ras andAKT converge to increase the activity of a key regulator of glycolysis, 6-phosphofructo-2-kinase (PFKFB3). This enzyme synthesizes fructose 2,6-bisphosphate (F26BP), which is an activator of 6-phosphofructo-1-kinase, a key step of glycolysis. Previously, a weak competitive inhibitor of PFKFB3,...
Mixed ligand complexes of copper (II), involving either Mercaptyl thiazolidinone (1) [2-(2hydroxy benzoyl)-3-N-(2-mercaptyl)-1-Thiazolidin-4-one] or Pyridine thiazolidinone (2) [ 2-(2hydroxy benzoyl-3-N-(2-Pyridinyl)-1-Thiazolidin-4-one] alone and along with Thiourea were synthesized by partial or complete replacement of the strongly coordinated ammonia of ammine complex. All the products have ...
The development of a functional disulfide, FmSSPy-A (Fm = 9-fluorenylmethyl; Py = pyridinyl), is reported. It can effectively convert small molecule and protein thiols (-SH) to form -S-SFm adducts under mild conditions. This method allows for a H2S-free and biomimetic protocol to generate highly reactive persulfides (in their anionic forms). The high nucleophilicity of persulfides toward a numb...
In the title mol-ecule, C20H18N2O3, an intra-molecular N-H⋯O hydrogen bond leads to a cis conformation of the pyridinyl-vinyl fragment. The phenyl and pyridine rings are inclined to one another by 77.3 (1) °. In the crystal, mol-ecules are linked via pairs of C-H⋯O hydrogen bonds, forming inversion dimers. The dimers are linked by C-H⋯O hydrogen bonds and C-H⋯π inter-actions, forming a three-di...
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