In the title salt, C(16)H(21)N(2)O(+)·Cl(-), the amide group makes a dihedral angle of 24.98 (2)° with respect to the pyridinium ring. In the crystal, both the amide and pyridinium N atoms are involved in N-H⋯Cl hydrogen bonding. Weak inter-molecular C-H⋯Cl and C-H⋯O inter-actions also occur.

The title structure, C(5)H(6)ClN(2) (+)·NO(3) (-), is held together by extensive hydrogen bonding between the NO(3) (-) ions and 2-amino-5-chloro-pyridinium H atoms. The cation-anion N-H⋯O hydrogen bonds link the ions into a zigzag- chain which develops parallel to the b axis. The structure may be compared with that of the related 2-amino-5-cyano-pyridinium nitrate.

In the crystal structure of the title compound, (C(5)H(6)N)(2)[UCl(4)O(2)]·C(4)H(8)O(2), the pyridinium cations occupy general positions and the anions and the solvent dioxane mol-ecule are located on centres of inversion. The dioxane mol-ecules are connected to two symmetry-related pyridinium cations via O-H⋯O hydrogen bonding. There are additional inter-molecular C-H⋯Cl contacts, which are in...

Biodegradable nanostructures displaying aggregation-induced emission (AIE) are desirable from a biomedical point of view, due to the advantageous features loading capacity, brightness, and fluorescence stability. Herein, biodegradable polymers comprising poly (ethylene glycol)-block-poly(caprolactone-gradient-trimethylene carbonate) (PEG-P(CLgTMC)), with tetraphenylethylene pyridinium-TMC (PAIE...

2-Dimethylalkylammonium pyridinium and 2-dimethylalkylammonium pyrimidinium ditriflate salts are very powerful methylating agents toward phosphorus (triphenylphosphine) and nitrogen (triethylamine) nucleophiles. In competition experiments with triethylamine as nucleophile, these N-methyl disalts are more reactive methylating agents than dimethyl sulfate. Reaction of the pyridinium dications wit...

Inhibition of synaptic acetylcholinesterase (AChE) by organophosphate (OP) nerve agents is the main reason for their toxicity. Oximes are used as antidotes to reactivate nerve agent-inhibited AChE. To understand the mechanism of oxime-induced reactivation, we generated several mutant AChEs. Reactivation studies conducted with wild-type and mutant AChEs revealed that the peripheral anionic site ...

The objective of this work was to evaluate the relationship between chemical reactivity of 3-substituted pyridinium salts and their cytotoxic properties against murine leukemia L1210. Chemical reactivity of pyridinium salts towards NADH oxidation following one-step hydride transfer depends strongly on their redox properties. The investigated reaction may reflect the ability of the salts to depl...

A rapid and accurate method for analyzing pyridinium oximes-N-methylpyridinium2-aldoxime chloride, N,N’-trimethylene-(pyridinium-4-aldoxime) dihalide, and N,N’oxydimethyl(pyridinium-4-aldoxime) dich bride-in plasma, urine, and whole blood is described.The method is completely automated and requires small sample volumes. Concentrations ranging from 3 to 120 Eq./L. in biologic fluids can be deter...