Promoter methylation status of O-6-methylguanine-DNA methyltransferase (MGMT), a DNA repair enzyme, is a critical biomarker in glioblastoma (GBM), as treatment decisions and clinical trial inclusion rely on its accurate assessment. However, interpretation of results is complicated by poor interassay reproducibility as well as a weak correlation between methylation status and expression levels o...

HYSYS process modeling software was used to analyze the effect of reflux ratio and number of trays on the purity of ethylene in a vapor recompression distillation column and also in an ordinary distillation column. Analysis of data showed that with increased pressure a higher reflux ratio is needed to obtain a purity of 99.9% for both towers. In addition number of trays was varied to see its ef...

Acetaldehyde is regulated as a toxic substance in various fields, and the method for monitoring or analysis of acetaldehyde is important. However, handling is difficult because of the high reactivity and low boiling point of acetaldehyde. Therefore, a reference material for high purity acetaldehyde with high accuracy was not available. Although the measuring method of acetaldehyde as a reagent ...

Recent efforts to partition the space of morality have focused on the descriptive content of distinct moral domains (e.g., harm versus purity), or alternatively, the relationship between the perpetrator and victim of moral violations. Across three studies, we demonstrate that harm and purity norms are relevant in distinct relational contexts. Moral judgments of purity violations, compared to ha...

We measured colorimetric purity thresholds as a function of stimulus duration for seven wavelengths between 430 and 650 nm. Purity thresholds were measured in a hue substitution mode. The purity-duration function showed decreasing purity as duration was increased to about 640 msec. Functions for different wavelengths could be fit by a fixed chromatic template displaced on the purity axis. Incre...

Many moral codes place a special emphasis on bodily purity, and manipulations that directly target bodily purity have been shown to influence a variety of moral judgments. Across two studies, we demonstrated that reminders of physical purity influence specific moral judgments regarding behaviors in the sexual domain as well as broad political attitudes. In Study 1, individuals in a public setti...