BACKGROUND The ability of the Naughton-Balke exercise treadmill test, an objective indicator of exercise capacity, to predict abnormal hemodynamics and mortality in pulmonary hypertension is unknown. METHODS AND RESULTS We performed a cohort study of 603 patients with pulmonary hypertension from 1982 to 2006, and studied the utility of exercise treadmill test as a predictor of abnormal hemody...

IN A PREVIOUS STUDY of the pulmonary capillary bed in mitral valve disease,' the mean value for pulmonary diffusing capacity for carbon monoxide (DL) was found to be significantly lower than normal, in agreement with several other reports.2 7 This was due mainly to impairment of the membrane diffusing capacity (DM). Reduction in pulmonary capillary blood volume (V,) was found only in patients w...

OBJECTIVES To assess the nature of pulmonary dysfunction in type 1 diabetes and the relationship of pulmonary function tests to diabetic factors and complication. SUBJECTS AND METHODS Sixteen type 1 diabetic patients and 26 control subjects matched for age and sex were studied. We performed spirometry measurements and measured pulmonary diffusing capacity (DL(CO)) in sitting and supine positi...

We studied the pulmonary function and ventilatory response to carbon dioxide and hypoxia in three sisters aged 16, 13, and 10 years who presented with droopy eyelids, external ophthalmoplegia, hearing loss, speech difficulty, and truncal muscular weakness. Pulmonary function test results showed decreased maximum static pressure, reduced vital capacity and total lung capacity, normal functional ...

The interpretation of the roentgenograph of pulmonary fibrosis in terms of functional respiratory disability is one of the most difficult problems which confronts the physician in industrial medicine. While the anatomical lesions of pulmonary fibrosis and their roentgenographic detection have been studied extensively, the mechanisms responsible for the respiratory disability are inadequately un...

conclusions inhalation of tiotropium bromide in combination with pulmonary rehabilitation could improve some plethysmographic lung volumes and clinical outcomes in patients with chronic pulmonary disease due to sm. short-term prescription of pulmonary rehabilitation has no effect on cpet of patients. patients and methods in a randomized clinical trial, using convenient sampling method, 54 patie...

The pulmonary diffusing capacity for carbon monoxide was measured by single breath (DcoSB) and steady state (DcoSS) techniques in 48 patients with various pulmonary circulatory disorders and the results compared with the type of hemodynamic abnormality. Patients with pure inflow obstruction (primary pulmonary hypertension, recurrent pulmonary emboli) had the lowest Dco (mean DcoSB = 14.3 ml/min...