نتایج جستجو برای: ptm

تعداد نتایج: 1366  

2014
Min-Gang Su Kai-Yao Huang Cheng-Tsung Lu Hui-Ju Kao Ya-Han Chang Tzong-Yi Lee

Transmembrane (TM) proteins have crucial roles in various cellular processes. The location of post-translational modifications (PTMs) on TM proteins is associated with their functional roles in various cellular processes. Given the importance of PTMs in the functioning of TM proteins, this study developed topPTM (available online at http://topPTM.cse.yzu.edu.tw), a new dbPTM module that provide...

2013
Florian P. Breitwieser Jacques Colinge

UNLABELLED The establishment of extremely powerful proteomics platforms able to map thousands of modification sites, e.g. phosphorylations or acetylations, over entire proteomes calls for equally powerful software tools to effectively extract useful and reliable information from such complex datasets. We present a new quantitative PTM analysis platform aimed at processing iTRAQ or Tandem Mass T...

2012
Mona Haraty Diane Tam Shathel Haddad Joanna McGrenere Charlotte Tang

A plethora of electronic personal task management (e-PTM) tools have been designed to help individuals manage their tasks. There is a lack of evidence, however, on the extent to which these tools actually help. In addition, previous research has reported that e-PTM tools have low adoption rates. To understand the reasons for such poor adoption and to gain insight into individual differences in ...

2016
Taigo Kato Yoichi Kakuta Toyofumi Abe Kazuaki Yamanaka Ryoichi Imamura Masayoshi Okumi Naotsugu Ichimaru Shiro Takahara Norio Nonomura

The frequency of malignancy is increasing in kidney transplant recipients. Posttransplant malignancy (PTM) is a major cause of long-term graft survival inhibition. In this study, we evaluated the frequency and prognosis of PTM at our center and examined the efficacy of cancer screening. Between 1972 and 2013, 750 patients were followed-up at our center. Annual physical examinations and screenin...

Journal: :Cancer prevention research 2012
Yoshitsugu Obi Naotsugu Ichimaru Takayuki Hamano Kodo Tomida Isao Matsui Naohiko Fujii Masayoshi Okumi Jun-Ya Kaimori Koji Yazawa Yukito Kokado Yoshiharu Tsubakihara Norio Nonomura Hiromi Rakugi Shiro Takahara Yoshitaka Isaka

Posttransplant malignancy (PTM) is a limiting factor both for patient and allograft survival in kidney transplant recipients (KTRs). We hypothesized that active vitamin D compounds (AVD) could reduce PTM development in KTRs. Ambulatory KTRs in a Japanese prospective cohort were followed from August 2007 to November 2010. The outcome of interest was newly diagnosed PTM. A propensity score (PS) o...

Journal: :The Indian journal of medical research 2005
A B Sudeep R Khushiramani S S Athawale A C Mishra D T Mourya

BACKGROUND & OBJECTIVE Potato tuber moth (PTM), Phthorimaea operculella Zeller is a widely distributed, devastating pest of potatoes attacking the foliage and infest the tubers in both field and store causing serious economic damage. As application of PTM granulovirus (PTM-GV) has shown significant reduction in damage, attempts were made to develop a new cell line from this insect to grow PTM-G...

2010
Willem Flameng Marie-Christine Herregods Monique Vercalsteren Paul Herijgers Kris Bogaerts

Background—Prosthesis-patient mismatch (P-PtM) after aortic valve replacement results in disturbed valve performance associated with increased pressure gradients. However, it is unknown whether this can be related to future structural valve deterioration (SVD) of the bioprosthesis. Methods and Results—In 564 patients (mean age, 74 5 years) receiving an aortic valve bioprosthesis, clinical follo...

Journal: :Archives of surgery 2005
Jen-Der Lin Szu-Tah Chen Tzu-Chieh Chao Chuen Hsueh Hsiao-Fen Weng

HYPOTHESIS Total thyroidectomy followed by radioactive iodine I 131 treatment is effective in papillary thyroid microcarcinoma (PTM) with lymph node or extrathyroid invasion. DESIGN Retrospective study. SETTING Chang Gung Medical Center, Linkou, Taiwan. PATIENTS A total of 227 patients with PTM, categorized into high-risk (n = 12) and low-risk (n = 215) groups according to age, metastases...

2015
Michael R. Shortreed Craig D. Wenger Brian L. Frey Gloria M. Sheynkman Mark Scalf Mark P. Keller Alan D. Attie Lloyd M. Smith

Bottom-up proteomics database search algorithms used for peptide identification cannot comprehensively identify post-translational modifications (PTMs) in a single-pass because of high false discovery rates (FDRs). A new approach to database searching enables global PTM (G-PTM) identification by exclusively looking for curated PTMs, thereby avoiding the FDR penalty experienced during convention...

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