background: psoriasis is a disease which may have a direct impact on the psychological and social aspects of the patient, particularly due to its visibility. to date, we are unaware of any study showing a relationship between psoriasis and psychological parameters such as psychological vulnerability and coping strategies . objective: the aim of this study was to evaluate the effects of psoriasi...

Background: Psoriasis treatment is very important regard to mental sequeler and creating morbidity. First line treatment of generalized plaque type psoriasis includes methotrexate, phototherapy and retinoids. Objective: To compare bath-PUVA and acitretin in the treatment of generalized plaque type psoriasis. Patients and Methods: 40 patients with generalized plaque type psoriasis with PAS...

Background: Psoriasis is a common disease of the skin. Metabolic disorders have been suggested in the etiology of psoriasis. Objective: As hypocalcemia has been reported to provoke psoriasis, we studied the blood calcium level in this disease. Patients and Methods: In this case-control study, we measured blood calcium level in 120 psoriatic patients visited in outpatient clinic or admitte...

Background There is limited evidence detailing the cost-effectiveness of psoriasis treatments in the Asian region. Therefore, this study is aimed to evaluate the cost-effectiveness of 3 psoriasis treatments tailored for moderate to severe psoriasis, namely topical and phototherapy (TP), topical and systemic (TS), and topical and biologic (TB) regimens, respectively. Me...

Background: As a chronic inflammatory condition, psoriasis results from an interaction between genetic and immunologic factors in a predisposing environment. In spite of compelling evidence for the role of T cells and cytokines in psoriasis, interleukin (IL)- 10 and IL-22 have not been sufficiently investigated. Objective: To assess the serum levels of IL-10 and IL-22 in patients with psori...

Background: The reduction of disability caused by psoriasis is an important issue in dermatology. It is thus important to assess the patients’ appraisal of their quality of life. Objective: The aim of the present study was to assess quality of life among patients with psoriasis and to compare these estimates with general population. Patients and Methods: In this cross-sectional study, 55 ...

Background: Psoriasis is a chronic and recurrent inflammatory disease that involves skin, joints and different organ systems. It is associated with Multiple morbidities such as cardiovascular disorders, diabetes, hypertension, hyperlipidemia and chronic kidney disease (CKD). Due to the high importance of the association between psoriasis and CKD which results in major side effects the aim of th...