UNLABELLED Study Type - Diagnostic (exploratory cohort) Level of Evidence 2b What's known on the subject? and What does the study add? Due to sampling error, the Gleason score of clinically localized prostate cancer is frequently underestimated at the time of initial biopsy. Given that this may lead to inappropriate surveillance of patients with high-risk disease, there is considerable interest...

OBJECTIVE The aim was to determine the prognostic ability of Partin's tables for a patient collective undergoing radical prostatectomy (RP) and to evaluate the association of prostate-specific antigen (PSA) density (PSAD) and postoperative lymph node status. METHODS From 1999 to 2006, 393 consecutive patients underwent RP at our Urology department. Patients with Gleason scores < 6, clinical s...

PURPOSE To evaluate the predictive performance of various parameters derived from volume-adjusted prostate-specific antigen (PSA) values in detecting prostate cancer (PCa) and high-grade (Gleason score≥7) PCa according to treatment with a 5α-reductase inhibitor (5ARI). METHODS The results of 3,520 prostate biopsies performed between May 2006 and January 2013 were retrospectively assessed. Wit...

Abstract Introduction The European Association of Urology (EAU) recommends multiparametric MRI (mpMRI) prior to prostate biopsy for investigation cancer (CaP). Specifically, the mpMRI should be reported using Prostate Imaging Reporting and Data System (PIRADS) tool. Our study aims externally validate PIRADS tool over a multi-centre district general hospital. Method Retrospective review was perf...

Mục đích: Mô tả và so sánh giá trị của kháng nguyên đặc hiệu tuyến tiền liệt toàn phần (PSAt) với tỷ trọng (PSAd) trong chẩn đoán ung thư vùng chuyển tiếp (UTCTTTL). Đối tượng phương pháp nghiên cứu: Nghiên cứu mô trên 67 bệnh nhân nghi ngờ UTTTL (bằng lâm sàng hoặc xét nghiệm PSA, có cộng hưởng từ (CHT) TTL, được sinh thiết TTL dưới hướng dẫn siêu âm qua trực tràng tại Bệnh viện Đại Học Y Hà n...

OBJECTIVE: To determine cut-off values for prostate specific antigen density (PSAD) in diagnosing carcinoma symptomatic patients. METHODS: This cross sectional, observational study conducted at Department of Chemical Pathology and Endocrinology, Armed Forces Institute Pathology, Rawalpindi, Pakistan from June 2020 to May 2021. Symptomatic patients (309) having prostatic enlargement on ultrasoun...

OBJECTIVES To examine the treatment outcomes of the prostate cancer (PCa) patients treated by radical prostatectomy (RP) who could be good candidates for active surveillance (AS) and test the confidence and reliability of the AS criterias for predicting advanced stage disease (RP Gleason score≥7 or Pathological stage T3). METHODS Between 2005 and 2012 the records of the 401 patients who under...

Objective: Serum prostate-specific antigen (PSA) test is commonly applied for prostate cancer screening and diagnosis. However, the level of PSA varied in different races and can be influenced by many factors. Previous studies show that obese is related to the PSA level, but the results are highly inconsistent. The aim of this study was to examine the relationships among body mass index (BMI), ...

BACKGROUND Many urologic surgeons refer to biopsy core details for decision making in cases of localized prostate cancer (PCa) to determine whether an extended resection and/or lymph node dissection should be performed. Furthermore, recent reports emphasize the predictive value of prostate-specific antigen density (PSAD) for further risk stratification, not only for low-risk PCa, but also for i...