Background: Plasmapheresis is a well-recognised method for harvestingplasma.  It was introduced in the 1950s and is currently employed worldwide.  This method has been in use in Iran since 1979. Objective: To evaluate the efficacy of donor safety program used at the Iranian Blood Transfusion Organization. Methods: A comparison is made of the protein concentrations between the first-time and lon...

lentiviral vectors are among the promising viral based-vectors in gene therapy applications, but the efficiency of their targeting needs to be improved. (strept)avidin-biotin adaptor system is a novel approach to modify the lentiviral envelope for better targeting properties. herein, we describe utilization of this adaptor system by designing a candidate envelope protein-bearing biotin acceptor...

objective: the aim of this study was to construct a pcdna3.1+ vector containing fmdv type o/irn/1/2007-vp1 gene, protein expression in bhkt7 cells and evaluation of immune response in balb/c mice. materials and methods: fmdv type o/irn/1/2007 was isolated from a cattle in ray in 2007 and serotyped. the purified vp1 gene was sub-cloned into the ptz57r/t vector and pcdna3.1+ expression vector. t...

objective(s): production of a recombinant and immunogenic antigen using dengue virus type-3 envelope protein is a key point in dengue vaccine development and diagnostic researches. the goals of this study were providing a recombinant protein from dengue virus type-3 envelope protein and evaluation of its immunogenicity in mice. materials and methods: multiple amino acid sequences of different i...

Hazelnut (Corylus avellna L.) is one of the important nut crops in world. The harvesting ofhazelnuts is done either by hand or by manual or mechanical raking of fallen nuts in Iran.Common hazel is widely cultivated for its nuts, including in commercial orchards in Europe,Turkey, and Iran. There are some genotypes of hazelnut in Iran that their growing areas arelimited to Gillan, Aredbil, Mazand...

introduction: in some intoxicated patients, cerebrospinal fluid (csf) is examined due to the prolonged loss of consciousness, focal neurologic findings, and fever of unknown origin. we aimed to evaluate the probable relationship between the different toxicity causes and the csf indices in poisoned patients and determine if they could predict the patients’ outcome. methods: all patients who had ...

drought is one of the most important factors limiting crop yields around the world. drought stress in plants, the change (increase or decrease) in the production of plant proteins. this research was carried out using bread wheat genotypes. for evaluation of leaf protein pattern in wheat, 10 genotypes were assayed with 3 replications under irrigated (non-stress) and rain-fed (stress) conditions....

Synthesis of Trimethyl Chitosan Nanoparticles Containing Recombinant BLF1-stxB Protein Burkholderia Pseudomallei and Evaluation its Immunogenicity in Mice