thrombophilia is a pathological state of increased blood coagulability. it causes problems during pregnancy including preeclampsia, stillbirth, repeated abortions, and detached pair. out of the most prevalent factors causing inherited thrombophilia, protein s (prs), protein c (prc), and antithrombin iii (atiii) deficiency, and factor v leiden (fvl) mutation could be mentioned. this study aimed ...

Protein S deficiency is an autosomal dominant disorder that results from mutations in the protein S gene (PROS1). Inherited deficiency of protein S constitutes a risk factor for venous thromboembolism. Protein S functions as a nonenzymatic cofactor for activated protein C in the proteolytic degradation of coagulation factors Va and VIIIa. The frequency of protein S deficiency seems to differ be...

Background It has been reported that 15-20% of parous female have experienced at least one miscarriage, while 3% of them have experienced two miscarriages. The goal of this study was to evaluate the plasma level of coagulation factors in women with a history of spontaneous abortions. MaterialsAndMethods In this case-control study, 82 women with a history of two or more abortions referred to the...

Abstract Objective of the experiment was to study effect deficiency, adequate and excess dietary phosphorus supply on growth performance, retention utilisation phosphorus, length, mass geometry measurements femur shaft, content protein, ash, in viscera, edible (meat fat) inedible (bones skin) parts body pigs ageing from 33 110 days. It found that compared animals fed according requirement defic...

Background and objectives : Anemia prevalence, especially iron deficiency anemia, among Indonesian toddlers is high. Iron may interfere nerve development also cause immune problems. Protein malnutrition anemia. The prevalence higher in 6-23 months age group due to the increase need. However, correlations between protein intake with hemoglobin levels are still showing different results researche...

Severe protein C deficiency (i.e. protein C activity <1 IU dL(-1)) is a rare autosomal recessive disorder that usually presents in the neonatal period with purpura fulminans (PF) and severe disseminated intravascular coagulation (DIC), often with concomitant venous thromboembolism (VTE). Recurrent thrombotic episodes (PF, DIC, or VTE) are common. Homozygotes and compound heterozygotes often pos...

Background Given the relationship of vitamin D deficiency with insulin resistance syndrome as the component of polycystic ovary syndrome (PCOS), the main aim of this study was to compare serum level of 25- hydroxyvitamin D [25(OH)D] between PCOS patients and normal individuals. MaterialsAndMethods A cross sectional study was conducted to compare 25(OH)D level between117 normal and 125 untreated...