Protein is a very important part of a cell. It carries out its duties as specified by the information encoded in genes. Proteins interact with each other to carry out different biological functions. Information about these interactions will help a lot in understanding different diseases. Different classifiers have been used till now to classify the protein-protein interactions. Some of the clas...

Protein-protein interaction has proven to be a valuable biological knowledge and an initial point for understanding how the cell internally works. In this chapter, we introduce a novel approach termed STRIKE which uses String Kernel to predict protein-protein interaction. STRIKE classifies protein pairs into "interacting" and "non-interacting" sets based solely on amino acid sequence informatio...

background: prediction of interaction sites within the membrane protein complexes using the sequence data is of a great importance, because it would find applications in modification of molecules transport through membrane, signaling pathways and drug targets of many diseases. nevertheless, it has gained little attention from the protein structural bioinformatics community. methods: in this stu...