BACKGROUND Postmenopausal women experience adverse physiological changes caused by estrogen deprivation. Here, we hypothesized that the administration of isoflavone, a phytoestrogn, and/or physical exercise could reverse changes in the levels of hepatic enzymes disturbed by loss of estrogen to ameliorate postmenopause-related health problems. METHODS Thirty-week-old female Sprague-Dawley rats...

Objective(s) Several studies have reported improved response of exercised hearts to myocardial infarction (MI). This study was aimed to evaluate the preventive role of treadmill exercise and diosgenin on cardiac marker enzymes, thiobarbituric acid reactive substances (TBARS), total antioxidant status (TAS), lipids, and electrocardiographic (ECG) patterns in isoproterenol (ISO)-induced myocardi...

The phytohormone abscisic acid (ABA) plays a crucial role in mediating plant growth and development by recruiting genetically redundant ABA receptors. To overcome its oxidation inactivation, we developed a novel ABA analog named 2',3'-benzo-iso-ABA (iso-PhABA) and studied its function and structural characterization with A. thaliana ABA receptors. The (+)-iso-PhABA form showed much higher ABA-l...

The aim of this study was to determine the effect using peanut meal (Arachis hypogaea L.) instead soybean in rainbow trout (Oncorhynchus mykiss Walbaum, 1792) feeds on growth performance, biochemical composition and fillet color. For purpose, were fed for eight weeks with four different diets adjusted as iso-nitrogenic (45% protein), iso-lipidic (19% lipid) iso-energetic (22 kJ g-1). While CF (...

Die ISO27001:2005 als Informationssicherheitsmanagementsystem (ISMS) etabliert sich zunehmend als der Sicherheitsstandard in Unternehmen. Die Grundidee des ISMS basiert auf einem Management der Informationssicherheit welches ausgerichtet ist auf dem Management der Unternehmensrisiken und einen direkten Bezug zum Firmenumsatz herstellt. Bis September 2009 wurden weltweit mehr als 5822 1 zertifiz...

Isoproterenol (Iso) infusion for 48 h in rats decreases the ability of beta-adrenoceptor (beta-AR) agonists to increase alveolar liquid clearance (ALC). An impairment in protein kinase A (PKA) function appears to be critical in producing the desensitized ALC response. To test this hypothesis, we used a novel protein delivery reagent (Chariot, Active Motif) to deliver either the PKA catalytic su...

AIMS The beneficial effects of 4'-O-methylated flavonoids on induction of melanogenesis are well established. Here, we report the effect of isosakuranetin (Iso) on melanogenesis in B16BL6 melanoma cells and an analysis of the signaling pathways involved in this activity. METHODS B16BL6 melanoma cells were treated with several concentrations of Iso and melanin content was measured. Activation ...

Cardiac hypertrophy produced in vivo by pressure overload is characterized by selective up-regulation of the fetal/neonatal beta-cardiac myosin heavy chain (MHC) isogene. However, a molecular signal for beta-MHC isogene induction has not been identified. We examined cardiac MHC isogene expression in a cell culture model for hypertrophy. alpha-MHC and beta-MHC iso-protein and iso-mRNA levels in ...

this research was conducted to assess the effect of substituting corn for barley grain in diet on performance and reproductive characteristics of early lactating, holstein dairy cattle. a number of fifteen cows in their second lactation (26±11 dim) with 36.7±5.6 kg milk/d were investigated for 75 day (15 day for adaptation and 60 day for sampling) in a completely randomized design. the iso-ener...

One of the most regulated steps of translation initiation is the recruitment of mRNA by the translation machinery. In eukaryotes, this step is mediated by the 5'end cap-binding factor eIF4E bound to the bridge protein eIF4G and forming the eIF4F complex. In plants, different isoforms of eIF4E and eIF4G form the antigenically distinct eIF4F and eIF(iso)4F complexes proposed to mediate selective ...