Animal Prostate Carcinoma Models: Limited Potential for Vertebral Metastasis p. 151 A Model for Studies on Human Prostatic Carcinoma p. 159 Studies on the Pathogenesis of Osteoblastic Metastases by Prostate Cancer p. 165 Analysis of Bone Metastasis of Prostatic Adenocarcinoma in 137 Autopsy Cases p. 173 Nucleolar Organizer Regions in Prostate Cancer p. 183 Flow Cytometric Analysis of Prostatic ...

Introduction: Prostate cancer is the second common malignancy in men. Prostatic intraepithelial neoplasia (PIN) precursor lesion of prostatic carcinoma. Histopathological examination necessary to diagnose PIN lesions. Objective: The aim study determine incidence and analyse usefulness basal cell marker p63 expression various lesions prostate. Methods: This a two-year prospective 65 transurethra...

The somatostatin analogue (SA) Octreotide has been used as a therapeutic reagent for somatostatin receptor type 2a (SSTR2a)-positive cancers. The purpose of this study is to detect SSTR2a in human prostate carcinomas and to elucidate the effects of SA on SSTR2a-positive prostate carcinoma cells to determine the potential of this drug as a new therapeutic method for advanced prostate carcinoma. ...

Introduction: Benign Hyperplasia of the Prostate (BHP) and prostate cancer comprise about 90% all diseases gland. An increase in serum Specific Antigen (PSA) is an indicator underlying hyperplasia, inflammation, or cancer. Mast cells are found both inflamed tumour tissue. Aim: To find correlation mast cell count with age, weight prostate, PSA level, thereby distinguishing between benign inflamm...

Primary small cell carcinoma of the prostate is a rare and very aggressive disease with a poor prognosis, even in its localized form. We managed a case of primary small cell carcinoma of the prostate. The patient was treated with robot-assisted laparoscopic radical prostatectomy and adjuvant chemotherapy. Herein we report this first case of robot-assisted laparoscopic radical prostatectomy perf...

Although the amplified-in-breast cancer 1 (AIB1; SRC-3, ACTR, or NCoA3) was defined as a coactivator for androgen receptor (AR) by in vitro studies, its role in AR-mediated prostate development and prostate cancer remained unexplored. We report here that AIB1 is expressed in the basal and stromal cells but not in the epithelial cells of the normal mouse prostates. AIB1 deficiency only slightly ...

normal 0 false false false en-us x-none ar-sa background: prostate cancer is one of the most common cancer types both in western and eastern countries, involving mostly elder men. the mechanisms underlying the prostate cancer development remain unclear. prostate-specific antigen (psa) is the only well accepted marker for prostate cancer diagnosis and prognosis. the diagnosis and treatment of pr...

A monoclonal antibody (MAb) designated PD41 (IgG1k) was generated by hyperimmunizing BALB/c mice with a membrane preparation prepared from a moderately to poorly differentiated prostate carcinoma surgical specimen. The immunohistochemical reactivity of MAb PD41 was shown to be highly restricted to the ductal epithelia and secretions of prostate adenocarcinoma tissues. Sixty-five % of the prosta...

A 72-year-old male presented with urinary symptoms. His serum prostate specific antigen level was 65.2 ng/ml. His radical prostatectomy specimen showed clear cell lesion reminiscent of the clear cell renal cell carcinoma along with acinar type of prostatic adenocarcinoma, Gleason score 4 + 4. The lesional clear cells were positive for pancytokeratin, epithelial membrane antigen, CD10, vimentin,...

Objectives: To determine the pattern of histological findings in prostatic chips obtained from cases enlarged prostate gland and to correlate with PSA levels. Materials Methods: It was a cross sectional descriptive study conducted Northwest General Hospital , Peshawar 1st January 2018 23rd December 2021. A total 500 male features prostate, frequency, urgency dribbling mean age 52 ± 12.3 years (...