MOTIVATION Although the outbreak of the severe acute respiratory syndrome (SARS) is currently over, it is expected that it will return to attack human beings. A critical challenge to scientists from various disciplines worldwide is to study the specificity of cleavage activity of SARS-related coronavirus (SARS-CoV) and use the knowledge obtained from the study for effective inhibitor design to ...

The ecosystem health of rivers downstream of dams is among the issues that has become focus of attention of many researchers particularly in the recent years. This paper aims to deal with the question, how the environmental health of a river ecosystem can be addressed in water resources planning and management studies. In this study, different parameters affecting the ecosystem of river-reservo...

Resum This paper deals with an NP-hard string problem from the bio-informatics field: the repetition-free longest common subsequence problem. This problem has enjoyed an increasing interest in recent years, which has resulted in the application of several pure as well as hybrid metaheuristics. However, the literature lacks a comprehensive comparison between those approaches. Moreover, it has be...

Resum This paper deals with an NP-hard string problem from the bio-informatics field: the repetition-free longest common subsequence problem. This problem has enjoyed an increasing interest in recent years, which has resulted in the application of several pure as well as hybrid metaheuristics. However, the literature lacks a comprehensive comparison between those approaches. Moreover, it has be...

Resum This paper deals with an NP-hard string problem from the bio-informatics field: the repetition-free longest common subsequence problem. This problem has enjoyed an increasing interest in recent years, which has resulted in the application of several pure as well as hybrid metaheuristics. However, the literature lacks a comprehensive comparison between those approaches. Moreover, it has be...

In this work, we formulate a nonlinear programming model for the design of an integrated microalgaebased biorefinery for the production of biodiesel and value added co-products which depend on the particular microalgae species considered. The production of biogas by anaerobic digestion of the oil cake together with waste streams is included. The process scheme includes the possibility to use gl...

Resum This paper deals with an NP-hard string problem from the bio-informatics field: the repetition-free longest common subsequence problem. This problem has enjoyed an increasing interest in recent years, which has resulted in the application of several pure as well as hybrid metaheuristics. However, the literature lacks a comprehensive comparison between those approaches. Moreover, it has be...

The data of Semantic Web exist in machine readable format called RDF, in order to promote data exchange on the web based on their semantics. Due to the nature of biological data, bio-ontologies tend to be very large, distributed, and interconnected. Thus, maintaining constraints and enforcing data consistency become very challenging. In previous study, we conducted a pioneer study and presented...

7 Downstream processing of biofuels and bio-based chemicals represents a challenging problem for 8 process synthesis and optimization, due to the intrinsic nonideal thermodynamics of the liquid 9 mixtures derived from the (bio)chemical conversion of biomass. In this work, we propose a new 10 interface between the process simulator SimSci PRO/II and the optimization environment of GAMS 11 for th...