purpose: to compare the outcomes and complications of mitomycin-c (mmc) trabeculectomy and ahmed glaucoma implant (agi) for treatment of aphakic glaucoma following congenital cataract surgery in children £ 16 years of age. methods: in a randomized clinical trial, eligible children were randomly assigned to mmc trabeculectomy or agi. aphakia was due to previous anterior lensectomy and vitrectomy...

Despite being documented in medical history from over 2400 years ago, primary congenital glaucoma (PCG), being a disease with low incidence rate, remains a challenge to ophthalmologists. The article provides a broad overview on the pathophysiology and diagnostic approach to PCG with major emphasis on the treatment options of PCG. While reviewing on the well-established treatment options, namely...

Glaucoma is a leading cause of irreversible blindness in Canada. Congenital glaucoma usually manifests during the first years of life and is characterised by severe visual loss and autosomal recessive inheritance. Two disease loci, on chromosomes 1p36 and 2p21, have been associated with various forms of congenital glaucoma. A branch of a large six generation family from a consanguineous Amish c...

Background: Glaucoma is one of the most common causes of blindness and is usually associated with elevated intraocular pressure. In patients with primary open angle glau-coma the number of trabecular meshwork cells is decreased. Death of the trabecular meshwork cells may be a result of apoptosis. Objective: To investigate the aqueous humor levels of soluble Fas (sFas) and Fas-Ligand (sFasL) in ...

glaucoma is a major cause of blindness worldwide. a single nucleotide polymorphism of the mthfr gene (c677t) has been associated with susceptibility to this disease, although this is controversial in the last decade. in this study, the possible association between the mthfr c677t polymorphism and the risk of developing primary open angle (poag) and pseudoexfoliation glaucoma (pexg) was investig...

PURPOSE To quantify the long-term outcomes of congenital glaucoma and surgical success rates following pseudo 360-degree trabeculotomy surgery at Children's Medical Center in Dallas. PATIENTS AND METHODS An International Classification of Diseases (ICD-9) database was utilized for a retrospective chart review. Thirty-eight eyes of 24 who underwent primary trabeculotomy with a pseudo 360-degre...