Background & Objective: Allergies are manifested with a variety of signs and symptoms. In this study, the frequencies of asthma symptoms, allergic rhinitis, eczema, and related factors among 6- to 7-year-old schoolchildren were investigated. Materials & Methods: This cross-sectional study was carried out among schoolchildren of 35 elementary schools of Zanjan by using the International Study o...

the clinical behavior of asthma varies with age at onset. this study was undertaken to identify associated markers of adult-onset allergic asthma (age ≥20 years).this cross-sectional study compared two groups: 58 patients with asthma onset at <20 years and 66 with onset at ≥20 years. they were compared depending on results of clinical history, and body mass index (bmi), aeroallergen sensitizati...

background: black seed (bs) is used in traditional medicine as a therapy for a variety of diseases including allergic asthma. materials and methods: in the present study, anti-inflammatory and immunomodulatory effects of bs on cytokine gene expression, lung airway eosinophilia and goblet cell hyperplasia were examined in a mouse mice model of allergic asthma. groups of 6-week-old female balb/c ...

Allergic rhinitis is the most common cause of allergic diseases. The recent guidelines of Allergic Rhinitis and its Impact on Asthma (ARIA) group, classified it to intermittent (less than 4 days per week and for less than 4 weeks) and persistent (more than 4 days per week or lasting more than 4 weeks regardless of the number of days per week). The present study evaluates the patients with ARIA ...

Even though, the term 'allergy' first appeared in the medical literature in 1906, allergic diseases such as asthma, urticaria and eczema have been known for centuries, and their history dates back to antiquity.1 In the Middle Ages, 'rose fever' was a well-known entity with symptoms similar to hay fever.2The first description of the clinical symptoms of hay fever (seasonal allergic rhinitis) is ...

many patients with atopic eczema (ae) would “march” to develop allergic rhinitis (ar) and asthma. physicians, patients and their families often do not appreciate the significance of these diseases as co-morbidities of atopy. the aim of this study was to evaluate the prevalence and severity of airway atopies in patients with ae. ar and asthma severity were assessed in consecutive ae patients see...

IgE plays a key role in allergic reactions, particularly the early phase response. A humanized monoclonal anti-IgE antibody (omalizumab) that prevents IgE from binding to receptors on mast cells and basophils is undergoing clinical trials in a number of allergic diseases. Following intravenous or subcutaneous administration in humans, omalizumab has a long plasma elimination half-life (1± 4 wee...

Background. Some hemostatic disturbances are observed in patients with various clinical manifestations of atopy. Increased platelet activation in vivo has been shown in patients with chronic allergic asthma. Objectives. Investigation of selected parameters of platelet activity and fibrinolysis in patients with pollen allergy suffering from seasonal allergic rhinitis and concomitant asthma sympt...

Asthma: Allergic asthma is an episodic wheezing illness often beginning before the age of 20. It occurs in patients from families with other IgE mediated illnesses such as allergic rhinitis and eczema. Unless specific aggravating factors are present all the time, the patient enjoys normal breathing between attacks. A careful history identifies important etiologic factors. A history of seasonal ...