[reaction: see text]. The copper acetate mediated intramolecular O-arylation of phenols with phenylboronic acid pseudopeptides is the key step in the preparation of macrocyclic biphenyl ether hydroxamic acid inhibitors of collagenase 1 and gelatinases A and B. The intramolecular macrocyclization was found to be mild and tolerant of common chemical functionality. This methodology should provide ...

in multi-step organic syntheses, the protection and deprotection of tetrahydropyranyl (thp) ethers is one of the most frequently used methods. over the years, different methods have been used from various catalytic systems for the protection of hydroxyl groups as thp ethers and their deprotection. herein we have reported that various alcohols and phenols have been efficiently converted to the c...

A three-component 1,2-aminoarylation of vinyl ethers, enamides, ene-carbamates and thioethers by synergistic photoredox nickel catalysis is reported. 2,2,2-Trifluoroethoxy carbonyl protected α-amino-oxy acids are used as amidyl radical precursors. anti-Markovnikov addition the to alkene Ni-mediated radical/transition metal cross over lead corresponding product. The cascade, which can be conduct...

The preparation of a new type of derivatives of the naturally occurring antioxidant hydroxytyrosol is reported. Hydroxytyrosyl alkyl ethers were obtained in high yield by a three-step procedure starting from hydroxytyrosol isolated from olive oil waste waters. Preliminary results obtained by the Rancimat method have shown that these derivatives retain the high protective capacity of free hydrox...

Thermal rearrangement of propargyl naphthyl ethers produced naphthopyrans. In the presence of sodium methoxide, propargyl naphthyl ethers were converted easily to naphthofurans and naphthodifurans in good yields

In multi-step organic syntheses, the protection and deprotection of tetrahydropyranyl (THP) ethers is one of the most frequently used methods. Over the years, different methods have been used from various catalytic systems for the protection of hydroxyl groups as THP ethers and their deprotection. Herein we have reported that various alcohols and phenols have been efficiently converted to the c...

Xylan is a predominant hemicellulose component that is found in plants and in some algae. This polysaccharide is made from units of xylose (a pentose sugar). One promising source of xylan is oat spelt. This feedstock was used for the synthesis of two xylan ethers. To achieve water soluble products, we prepared dihydroxypropyl xylan as a non-ionic ether on the one hand, and carboxymethyl xylan a...

In this review, we describe direct and indirect photochemical approaches that have been developed for the preparation of phthalimide- and naphthalimide-based, lariat-type crown ethers. The direct route utilizes a strategy in which nitrogen-linked side chains containing polyethoxy-tethered phthalimides and naphthalimides, possessing terminal α-trialkylsilyl groups, are synthesized utilizing conc...

in multi-step organic syntheses, the protection and deprotection of tetrahydropyranyl (thp) ethers is one of the most frequently used methods. over the years, different methods have been used from various catalytic systems for the protection of hydroxyl groups as thp ethers and their deprotection. herein we have reported that various alcohols and phenols have been efficiently converted to the c...