placental site trophoblastic tumor (pstt) is a very rare variant of gestational trophoblastic tumor. it can occur after normal termination of pregnancy or spontaneous abortion and ectopic or molar pregnancy. there is a wide range of clinical manifestations from a benign condition to an aggressive disease with fatal outcome. one of the most important characteristics of pstt, unlike other forms o...

The improved management of pituitary adenomas has led to an increasing number of pregnancies in patients harboring pituitary adenomas. Therefore, adequate management of pregnant women with pituitary adenomas is of growing importance. Because pregnancy produces several physiologic changes to the endocrine system, especially to the pituitary gland, endocrinologists must be knowledgeable and skill...

Treatment for metastatic gastrointestinal stromal tumor (GIST) is a challenge, particularly in pregnant female because of the absence of safety data concerning imatinib use during pregnancy. We report a case of metastatic GIST surgically resected during pregnancy with a favorable outcome. A treatment strategy for GIST in pregnant patients should be carefully discussed by a multidisciplinary tea...

INTRODUCTION Paraganglioma is an extremely rare catecholamine-producing tumor during pregnancy. Paraganglioma carries high risks of fetal and maternal mortality during pregnancy. We report a pregnant woman with paraganglioma in the second trimester. CASE DESCRIPTION A 24-year-old pregnant woman presented with severe hypertension in the 17th week of gestation. Hormonal examination and Magnetic...

OBJECTIVE Pregnancy represents a favorable condition for the development of thyroid nodules, likely due to the secretion of hormones with stimulatory activity. In particular, differentiated thyroid cancer (DTC) represents the second most frequent tumor among those diagnosed during pregnancy. However, few and discordant data are available about the impact of pregnancy on tumor outcome. METHODS...

BACKGROUND Desmoplastic small round cell tumor (DSRCT) is an extremely rare sarcomatous tumor, which is most commonly seen in men. Clinicians managing a patient with a rapidly enlarging mass in pregnancy should be aware of the risk for malignancy. CASE A 31-year-old woman was found to have a newly enlarged ovarian mass in the second trimester. She subsequently underwent a laparotomy for remov...

background and purpose: breast cancer is the most common cause of cancer-specific mortality among women worldwide. this study aimed at investigating the epidemiological, clinical, and pathological characteristics of breast cancer among patients attending baghban clinic in sari. materials and methods: the patients’ records (2008-2014) were used and data including age, gender, marital status, men...

objective: prolactinomas are the most common pituitary tumors in pregnant women. we conducted this study on pregnant women with prolactinoma to determine their clinical symptoms and signs and eventual necessity to medical therapy. materials and methods: a descriptive study was performed on 85 pregnant women with prolactinoma.patients were followed up by physical examination, imaging, and perime...

Background: Neurofibromatosis type 2 (NF2) is an autosomal dominant disease due to chromosome 22 (22q12.2) mutation with a prevalence of 1:33,000-40,000. As many as 50% cases are familial, 30-60% genetic mosaic, de novo mutations. Tumor growth in NF often becomes more rapid pregnancy. Pregnancy NF2 has risk complications hypertension, preeclampsia, cardiovascular pro...

OBJECTIVE To analyze the presentation, follow-up and evolution of differentiated thyroid cancer (DTC) detected during pregnancy. SUBJECTS AND METHODS Twenty nine women with DTC detected during pregnancy were analyzed. Group I (n = 13) was seen during pregnancy and DTC was diagnosed during gestation; detection of the nodule occurred during pregnancy (first trimester). Group II (n = 16) was see...